"It's a whole new cancer world" and "I don't remember what it's like to have sleep" were the most common themes of mothers interviewed by University of Colorado Cancer Center researchers during the maintenance period after a child's treatment for acute lymphoblastic leukemia (ALL). Results of this qualitative study are published in a recent issue of the Journal of Pediatric Nursing.
Mindfulness-based meditation 'benefits teen cancer patients'
3/14/2014
Past research has hailed meditation for its effects against pain, anxiety and depression. Now, new research from the University of Montreal in Canada suggests that mindfulness-based meditation may improve mood and sleep quality for teenage cancer patients.The findings were presented at the American Psychosomatic Meeting in San Francisco, CA.
Novel combination of 2 agents eradicates solid tumors in preclinical studies
3/14/2014
Researchers in the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute eradicated solid tumors in laboratory mice using a novel combination of two targeted agents. These two synergistic therapies stimulate an immune response, ultimately allowing solid tumors to act as their own cancer-fighting vaccine.
Tumor-preventing protein complex uncovered
3/14/2014
A team of researchers from Duke-NUS Graduate Medical School have discovered a protein complex that disrupts the process known as dedifferentiation (1), known to promote tumor development.Dedifferentiation (reversion) is a process that leads progenitor (2) or mature cells to become 'ectopic neural stem cells' which causes tumors.
Potential new drug targets for aggressive form of lung cancer
3/13/2014
Small cell lung cancer is an aggressive, highly lethal form of the disease that is linked with tobacco use. Researchers have now found mutations and other genetic interruptions occurring in the cancer's development that could translate to potential new drug targets for this disease.
UC Davis researchers one step closer to ovarian cancer marker
3/13/2014
The hunt is on to find biomarkers that detect cancer, but it's a challenging process. Early successes often are followed by heartbreaking failures. But now, researchers at UC Davis have verified that glycans (sugars attached to proteins) can be used to detect ovarian cancer. The study was published online in the journal Cancer Epidemiology, Biomarkers & Prevention.
Because of results seen in flat lab dishes, biologists have believed that cancers cells move through the body in a slow, aimless fashion, resembling an intoxicated person who cannot walk three steps in a straight line.
Targeting tumor-causing protein with antibody
3/13/2014
Cincinnati Cancer Center (CCC) and University of Cincinnati (UC) Cancer Institute researchers have found in a phase-1 study that patients with advanced melanoma and kidney cancer who were treated with a certain antibody that targets a tumor-enhancing protein was safe, which could lead to more treatment options for patients.
Bladder cancer patient with rare genetic mutations shows exceptional response to everolimus
3/13/2014
A patient with advanced bladder cancer experienced a complete response for 14 months to the drug combination everolimus and pazopanib in a phase I trial, and genomic profiling of his tumor revealed two alterations that may have caused this exceptional response, according to a study published in Cancer Discovery, a journal of the American Association for Cancer Research.
Quality of recovery improved by anesthetic technique for breast cancer surgery
3/13/2014
Anesthesiologists using a technique similar to a dental freeze can improve the quality of recovery and decrease recovery time for breast cancer surgery patients, according to a new study.The study, from researchers at St. Michael's Hospital and Women's College Hospital, was published in the March edition of Anesthesiology.