The loss of a cell protein favors cancer cells while harming healthy cells
6/03/2014
Janus kinases (JAKs) are proteins that can promote the growth of cancer cells. The protein JAK2 is of special therapeutic significance: its inactivation is believed to destroy cancer cells.
Identification of mechanisms of ibrutinib resistance in chronic lymphocytic leukemia
6/03/2014
A new study has discovered how resistance develops in patients taking ibrutinib, a new and highly effective drug for the treatment of chronic lymphocytic leukemia (CLL).
Overall survival benefit shown for patients with stage III soft tissue sarcomas
6/03/2014
Fox Chase Cancer Center researchers have carried out the first retrospective analysis of adjuvant chemotherapy's impact on overall survival in patients with stage III soft tissue sarcomas (STS)...
Bladder cancer patients carrying three specific mutations benefit from early chemotherapy
6/03/2014
Three genetic changes can predict whether a patient will benefit from chemotherapy before surgery to remove bladder cancer, according to new findings presented by Fox Chase Cancer Center researchers...
For some, screening for colorectal cancer should continue well past age 75
6/02/2014
Colorectal cancer (CRC) screening is cost-effective in elderly patients and should continue well past age 75 for those who have not already been screened, according to an article being published in...
Smokers with BRCA2 gene mutation 'have increased lung cancer risk'
6/02/2014
New research from The Institute of Cancer Research in the UK finds that smokers with a BRCA2 gene mutation have a 1 in 4 chance of developing lung cancer in their lifetime.
Men with metastatic prostate cancer may live longer with chemo first
6/02/2014
Giving chemo with hormone therapy instead of waiting for tumors to become resistant to hormone-blockers may prolong survival in metastatic hormone-sensitive prostate cancer.
Green tea component upsets cancer cell metabolism
6/02/2014
New study shows how a major biological active constituent of green tea changes the metabolism of pancreatic cancer cells by suppressing an enzyme associated with cancer.
FDA to require warnings on sunlamp products
6/02/2014
The U.S. Food and Drug Administration has issued a final order reclassifying sunlamp products and ultraviolet (UV) lamps intended for use in sunlamp products from low-risk (class I) to...
A 1 in 4 chance of developing lung cancer for smokers with gene defect
6/02/2014
Around a quarter of smokers who carry a defect in the BRCA2 gene will develop lung cancer at some point in their lifetime, a large-scale, international study reveals.