Endocrine-disrupting chemicals -- threatening fertility in industrialized countries
12/11/2015
The birth rate is declining in all industrialised countries, and socioeconomic factors and women's age are not solely to blame.
Researchers discover new aspect of gene regulation and possible target for cancer drugs
12/11/2015
There are about 20,000 genes in the human genome, but not all are used in all cells at all times. At any given moment, a cell is converting only roughly half its genes into proteins.
Why does tamoxifen not work in some women with hormone-sensitive breast cancer?
12/11/2015
Researchers suggest the reason tamoxifen does not work in some women with hormone-sensitive breast cancer could be because there is more than one single genetic marker involved.
Scientists identify effective and novel mechanisms to block chikungunya virus
12/11/2015
Scientists looking at the antiviral mechanisms of two previously identified human monoclonal antibodies have found they potently inhibit chikungunya virus (CHIKV) at multiple stages of infection.
First look at how astrocytes function in humans
12/11/2015
Pretty much everything happening in the brain would fail without astrocytes.
Breast cancer clinical trial of laser ablation treatment shows promising results for patients
12/10/2015
A laser treatment called Novilase® Breast Therapy shows promise as a way to successfully treat small breast cancers, according to research that was led by principal investigator Barbara...
ELOQUENT-2 trial, the open-label phase III study randomised 646 patients with relapsed/refractory multiple myeloma to elotuzumab in combination with lenalidomide and dexamethasone (ERd) (n = 321) or...
Data from Actimab-A phase 1 clinical trial for Acute Myeloid Leukemia presented
12/10/2015
Complete remission rate of 29% seen in the three highest dose cohorts, favorable safety and tolerability reported. Actinium Pharmaceuticals, Inc.
Blood samples analysis finds ESR1 gene mutations prevalent, associated with worse overall survival
12/10/2015
The different mutations may predict different responses to everolimus.Among patients with estrogen receptor (ER)-positive, metastatic breast cancer, those who had a D538G and/or a Y537S mutation in...
Breast-conserving therapy yielded better outcomes than mastectomy for early-stage patients
12/10/2015
Among patients with early-stage breast cancer, those who received breast- conserving surgery plus radiation therapy had improved overall survival after 10 years compared with those who received...