Missing DNA 'Mechanic' Key Driver In Lymphomas
5/17/2011
Cancer Research UK scientists have discovered how a protein in immune cells plays an essential role in their development by repairing DNA damage - and if this protein is missing lymphomas can form. The research, published online in Cancer Cell today1, showed that the protein, called ATMIN, acts as a cell's 'mechanic' looking out for damage in DNA...
MDxHealth's Methylation Tests Detect Prostate Cancer In Patients Deemed Low Risk By Pathology
5/17/2011
MDxHealth SA (NYSE Euronext: MDXH), a leading molecular diagnostics company in the field of personalized cancer treatment, today announced the results from a collaborative study demonstrating that changes in DNA methylation patterns in adjacent benign tissue could predict the presence of prostate cancer not detected or missed using standard histopathology...
Teva Pharmaceutical Industries Ltd. (NASDAQ: TEVA) and CureTech, a portfolio company of Teva and Clal Biotechnology Industries announced today preliminary topline results for CT-011, an investigational anti-PD-1 monoclonal antibody...
National Blood Cancer Charity Launches Unique National Clinical Trial Network
5/17/2011
A national blood cancer charity today launches a unique network of clinical trial centres with access to up to £50 million worth of new life-saving drugs, in response to current poor survival rates for many types of leukaemia, lymphoma and myeloma...
Over-Activation Of A Single Gene Promotes Leukemia, But Its Loss Causes Liver Cancer
5/17/2011
An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development of leukemia also acts to prevent cancer of the liver...
Discovery Of New Biomarker That Predicts Breast Cancer Relapse
5/17/2011
Researchers from Virginia Commonwealth University Massey Cancer Center have discovered a new biomarker related to the body's immune system that can predict a breast cancer patients' risk of cancer recurrence. This breakthrough may lead to new genetic testing that further personalizes breast cancer care...
Extending The Effectiveness Of Anticancer Drugs
5/17/2011
Today's anticancer drugs often work wonders against malignancies, but sometimes tumors become resistant to the effects of such drugs, and treatment fails. Medical researchers would like to find ways of counteracting such resistance, but first they must understand why and how it happens...
Researchers Are Laying The Foundation For A Future Blood Test For Early Detection Of Lung Cancer
5/17/2011
Scientists working with Professor Dr. Joachim L. Schultze have identified over 480 molecules whose concentration in the blood changes when a person develops lung cancer. These molecules are present in the blood cells either in increased or decreased quantities. "In lung cancer patients, typical patterns which can be detected with a measuring program thus emerge", explains Prof. Schultze...
A new test for prostate cancer that measures levels of prostate specific antigen (PSA) as well as six specific antibodies found in the blood of men with the disease was more sensitive and more specific than the conventional PSA test used today, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center...
Accounting For Temporal Changes In Health Practices When Calibrating Models
5/17/2011
The introduction and subsequent widespread use of the Papanicolaou (Pap) test has considerably reduced rates of cervical cancer in the last 50 years...