By using mice lacking a crucial gene that controls the process of chromatin remodeling of cytokines including those responsible for inflammation and comparing them to normal wild type mice with the gene, researchers at the George Washington University School of Medicine and Health Sciences have shown that the gene, Mta1, is essential for the parasite Schistosoma haematobium to ...
Biovest International, Inc. (OTCQB:BVTI), a majority-owned subsidiary of Accentia Biopharmaceuticals, Inc. (OTCQB:ABPI), today announced that BiovaxID®, Biovest's late-stage, autologous, active immunotherapy for the treatment of non-Hodgkin's lymphoma, was featured in an article published in the online version of the peer-reviewed journal, Journal of Clinical Oncology...
Asian Lung Cancer Patients Outlive Caucasians
6/02/2011
Asian non-small cell lung cancer (NSCLC) patients survive longer than Caucasians no matter how many drugs are given in a first-line setting, and the effect was apparent both before and after the introduction of targeted therapies in the early 2000s, according to research published in the June issue of the Journal of Thoracic Oncology...
Prostate Cancer, Chronic Fatigue Not Linked To XMRV Virus
6/02/2011
A study that includes authors at UC Davis has found that a retrovirus associated with prostate cancer tumors and chronic fatigue syndrome that evolved in laboratory mice less than two decades ago is unlikely to be widespread in humans and the cause of either disease. The study of the retrovirus, xenotropic murine leukemia virus-related virus, or XMRV, appears online in the journal Science...
The Internet Reveals Disconnect Between Medical And Lay Expertise
6/02/2011
The Internet is empowering its users more than ever, but the same technology that allows people access to limitless information has also enabled some to combat scientific or medical authority with their personal experiences...
Reducing Kidney Toxicity, A Severe Side Effect Of A Common Anticancer Drug
6/02/2011
Cisplatin is one of the most widely used anticancer chemotherapeutics. However, it has some severe side effects in normal tissues, in particular it is toxic to the kidneys. Understanding the mechanisms underlying this toxicity could identify targets for drugs that could be given together with cisplatin to protect the kidney during chemotherapy...
Oregon Health & Science University Knight Cancer Institute researchers uncovered a gene that may be the key to helping kidney cancer patients who don't respond to current therapies. This discovery could also provide a toolkit to identify patients who are most likely to benefit from drugs that block this gene from causing cancer cells to grow...
News From The Journal Of Clinical Investigation: June 1, 2011
6/02/2011
ONCOLOGY: Subdivisions reveal effective therapies in triple-negative breast cancer Breast cancers can be divided into different types based on several criteria, including the marker proteins they express...
Genetic analysis of the tumors from patients with advanced melanoma can clue researchers in to how well patients will respond to a therapy that targets the growth-promoting protein called BRAF, a researcher from the Perelman School of Medicine at the University of Pennsylvania will report on Monday, June 6 at the annual meeting of the American Society of Clinical Oncology...
Therapeutic Melanoma Vaccine Improves Response Rate, Progression-Free Survival
6/02/2011
A vaccine for one of the most lethal cancers, advanced melanoma, has improved response rate and progression-free survival for patients when combined with the immunotherapy drug Interleukin-2, according to research led by scientists from The University of Texas MD Anderson Cancer Center and Indiana University Health Goshen Center for Cancer Care...