Drug Targets Six Antigens Found In Brain Tumors And Three Found In Cancer Stem Cells, Prolonging Survival
6/17/2011

An experimental vaccine developed by researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute targets overactive antigens in highly aggressive brain tumors and improves length of survival in newly diagnosed patients, according to new data that was presented in a poster session at the 47th Annual Meeting of the American Society of Clinical Oncology...

Identification Of Protein That Improves DNA Repair Under Stress Could Lead To Treatments To Prevent Premature Aging And Cancer
6/17/2011

Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage...

New Weapon In The Fight Against Cancer: Radionuclide Treatment Against Small Tumors And Metastases
6/17/2011

A cancer diagnosis is not necessarily a death sentence. There are now quite a number of possibilities to treat cancer. In addition to radiotherapy and chemotherapy, so-called radionuclide treatment has also become an important component in the fight against the mutated cells. It involves injecting radioactive elements, so-called nuclides, into the patient's circulatory system...

Researchers Identify Key Molecule Of Stem Cells In Human Glioblastoma Cells
6/17/2011

Professor Günther Schütz of the German Cancer Research Center (DKFZ) in Heidelberg and Professor Peter Lichter (also DKFZ) recently identified a specific molecule on brain stem cells - the protein Tlx. It is a transcription factor which stimulates the activity of specific genes, inducing normal NSCs to migrate from their niche and develop into healthy neurons...

FDA Grants Accelerated Approval Of ISTODAX(R) As Treatment For Patients With Peripheral T-Cell Lymphoma Who Have Received At Least One Prior Therapy
6/17/2011

Celgene Corporation (Nasdaq:CELG) today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval for its Supplemental New Drug Application (sNDA) for an additional indication for ISTODAX (romidepsin) for injection for the treatment of peripheral T-cell lymphoma (PTCL) in patients who have received at least one prior therapy...

Melanoma Screening May Be Most Effective In Older Patients With Risk Factors
6/17/2011

Dermatologists are most likely to discover melanomas in patients ages 50 years or older with a personal history of skin cancer or a family history of melanoma, according to a report in the June issue of Archives of Dermatology, one of the JAMA/Archives journals. As background, the article notes that melanoma is a fairly common and serious cancer, with death rates correlating to advancing age...

Deprivation Leads To Over 2,600 Cancer Deaths A Year, UK
6/17/2011

More than 2,600 deaths in England from some of the most common types of cancer could be avoided each year if all cancer patients had the same chance of survival as the most affluent section of society, a new piece of research suggests...

Continued Progress In Reducing Cancer Mortality, American Cancer Society Report Finds
6/17/2011

A steady reduction in overall cancer death rates translates to the avoidance of about 898,000 deaths from cancer between 1990 and 2007, according to the latest statistics from the American Cancer Society. However, the report, Cancer Statistics 2011, and its companion consumer publication Cancer Facts & Figures 2011 find that progress has not benefitted all segments of the population equally...

Cancer Care Completely Omitted From New ACO Rule
6/17/2011

The Community Oncology Alliance (COA) has submitted comments to the Centers for Medicare and Medicaid Services (CMS) about the proposed rule governing the creation of accountable care organizations (ACOs) under the federal health reform law. CMS recently published the proposed rule to implement the Medicare Shared Savings Program...

UC Davis Researchers Develop Tool To Help Assess Surgical Risk In Terminally Ill Cancer Patients
6/17/2011

Physicians and their patients with late-stage cancer now have a tool to help them decide if surgery is the best choice. Often recommended to alleviate pain or other cancer complications, surgery for those with less than six months to live carries significant risks. Many will die as a result of an operation...