In Breast Cancer, False Negative Tests May Lead To Wrong Treatment
6/28/2011
A team of Yale Cancer Center researchers has confirmed that between 10-20% of breast cancers classified as Estrogen Receptor (ER) negative are really positive. Understanding when and why breast cancers may be misclassified has important implications for treatment and outcomes for women diagnosed with breast cancer. Its findings are published online in the June 28 Journal of Clinical Oncology...
New Clues To How Cancer Spreads
6/28/2011
Cancer cells circulating in the blood carry newly identified proteins that could be screened to improve prognostic tests and suggest targets for therapies, report scientists at the Duke Cancer Institute...
Potent Antiplatelet Drug Effective With Low-Dose Aspirin
6/28/2011
When taken with higher doses of aspirin (more than 300 milligrams), the experimental antiplatelet drug ticagrelor was associated with worse outcomes than the standard drug, clopidogrel, but the opposite was true with lower doses of aspirin...
Melanoma Risks May Be Reduced In Some Women By Calcium And Vitamin D
6/28/2011
A combination of calcium and vitamin D may cut the chance of melanoma in half for some women at high risk of developing this life-threatening skin cancer, according to a new study by Stanford University School of Medicine researchers...
Johns Hopkins University and Innogene Kalbiotech today launched a Phase III randomised controlled clinical trial on a novel therapeutic cancer vaccine to treat Stage III and Stage IV lung cancer. The clinical trial, to be completed in five years, will involve more than 40 institutions worldwide, including Singapore,Indonesia, Malaysia, the Philippines, and Thailand...
Potent Breast Cancer Tumor Suppressor Identified
6/28/2011
Researchers have identified the gene-regulating protein Runx3 as a potent suppressor of tumor growth in breast cancer and found that it most likely does this by regulating cellular response to circulating estrogen, the process behind estrogen-receptor positive (ER-positive) breast cancers, which account for over 70% of human breast cancers...
Study Finds Mammography Screening Reduces Breast Cancer Mortality
6/28/2011
Breast cancer screening with mammography results in a significant reduction in breast cancer mortality, according to long-term follow-up results of a large-scale Swedish trial. The results are published online in the journal Radiology. "Mammographic screening confers a substantial relative and absolute reduction in breast cancer mortality risk in the long-term," said Stephen W. Duffy, M.Sc...
Nearly Half Of Women With Advanced Breast Cancer In The U.S. Not Receiving Lifesaving Treatment
6/28/2011
Forty-five percent of women with advanced breast cancer in the U.S. did not receive postmastectomy radiation therapy (PMRT) despite the publication of evidence-based guidelines outlining PMRT as a potentially lifesaving treatment, according to new research from The University of Texas MD Anderson Cancer Center...
Cancer Genetics Expert Chi Van Dang To Lead Penn Medicine's Abramson Cancer Center
6/28/2011
Chi Van Dang, MD, PhD, a renowned cancer biologist and hematologist-oncologist, has been appointed director of the Abramson Cancer Center of the University of Pennsylvania, effective September 1, 2011. Dr. Dang is currently a professor at The Johns Hopkins University School of Medicine in the departments of Medicine, Cell Biology, Oncology, Pathology, and Molecular Biology & Genetics...
Childhood Cancer Survivors Are At High Risk For Multiple Tumors As They Age
6/28/2011
The largest study yet of adult childhood cancer survivors found that the first cancer is just the beginning of a lifelong battle against different forms of the disease for about 10 percent of these survivors. The research involved 14,358 individuals enrolled in the federally funded Childhood Cancer Survivor Study (CCSS). St...