Triple-Negative Breast Cancer Subtypes Respond To Different Therapies
6/30/2011
Vanderbilt-Ingram Cancer Center researchers have identified six subtypes of an aggressive and difficult-to-treat form of breast cancer, called "triple-negative breast cancer (TNBC)." In the July issue of the Journal of Clinical Investigation, Cancer Center Director Jennifer Pietenpol, Ph.D...
Improving Efficacy Of Drugs For Bladder Cancer Would Boost Post-Surgery Survivorship
6/30/2011
Researchers at the UC Davis Cancer Center have discovered a way of sensitizing muscle-invasive bladder cancer cells so that they succumb to the toxic effects of chemotherapy. The finding adds to mounting evidence that tiny strands of RNA - called microRNA - play key roles in some of the deadliest types of cancer...
New Therapy For Childhood Neuroblastoma Proves Feasible And Safe
6/30/2011
A new treatment option may soon be available for children with neuroblastoma according to research published in the July issue of The Journal of Nuclear Medicine...
Detailed Ovarian Cancer Analysis Completed By The Cancer Genome Atlas
6/30/2011
An analysis of genomic changes in ovarian cancer has provided the most comprehensive and integrated view of cancer genes for any cancer type to date. Ovarian serous adenocarcinoma tumors from 500 patients were examined by The Cancer Genome Atlas (TCGA) Research Network and analyses are reported in the June 30, 2011, issue of Nature...
ASCO Statement On Publication Of The National Lung Screening Trial Results
6/30/2011
Following is a statement for attribution from Bruce Johnson, MD, a Board Member of the American Society of Clinical Oncology (ASCO), and lung cancer expert with the Dana-Farber Cancer Institute, on The New England Journal of Medicine's publication of the results of the National Lung Screening Trial (NLST)...
Evolution Of Skin And Ovarian Cancer Cells Decoded
6/30/2011
A team of researchers led by scientists at the University of California, San Francisco has developed a way to uncover the evolution of human cancer cells, determining the order in which mutations emerge in them as they wend their way from a normal, healthy state into invasive, malignant masses...
Screening With CT Scans Reduces Lung Cancer Deaths
6/30/2011
Results of the National Lung Screening Trial (NLST) published online in the June 30 New England Journal of Medicine report a twenty percent reduction in lung cancer deaths among study participants who were screened with low-dose helical computed tomography (CT) versus those screened with chest X-ray...
American Lung Association Responds To Results Of National Lung Screening Trial
6/30/2011
The American Lung Association is optimistic about the promising results of the National Cancer Institute's National Lung Screening Trial, which indicate low-dose CT scans can have significant impact on lung cancer mortality...
Is Bevacizumab Cost-Effective In Lung Cancer?
6/30/2011
An economic analysis of the drug Bevacizumab showed that this drug is not cost-effective when given with chemotherapy for advanced non-small cell lung cancer. The goal of the study was to determine if bevacizumab is cost-effective when given in combination with standard chemotherapy to patients with advanced non-small cell lung cancer...
Avastin Not Suitable For Breast Cancer Says FDA Panel
6/30/2011
A panel of experts that advises the US Food and Drug Administration (FDA) concluded on Wednesday that the cancer drug Avastin, generic name bevacizumab, is not a suitable treatment for breast cancer and recommended the FDA withdraw its approval of the drug for such use. The FDA does not have to follow the recommendations of its advisory committees, but it usually does...