Researchers Develop Compound To Block Signaling Of Cancer-Causing Protein
7/18/2011
Researchers at New York University's Department of Chemistry and NYU Langone Medical Center have developed a compound that blocks signaling from a protein implicated in many types of cancer. The compound is described in the latest issue of the journal Nature Chemical Biology. The researchers examined signaling by receptor tyrosine kinase (RTK)...
In HER2-Postive Breast And Brain Cancer Patients Trastuzumab And Chemotherapy Improved Survival
7/18/2011
The use of trastuzumab, chemotherapy and surgery among women with HER2-positive metastatic breast cancer significantly improved survival from the time central nervous system metastases were diagnosed. Based on these study results, lead researcher Adam Brufsky, M.D., Ph.D...
Lymphoma Drug Shrinks Tumors In Dogs, Could Lead To Human Treatment
7/18/2011
There are many kinds of cancers of the immune system, but one, Activated B-Cell Diffuse Large B-Cell Lymphoma, or ABC-DLBCL, is particularly common and pernicious...
Cancer Rates Rise In Middle-Aged, UK
7/18/2011
Cancer rates in middle-aged men and women in Great Britain have gone up by nearly 20 per cent in a generation - an increase of 17,000 cases a year - according to new figures released today (Monday) by Cancer Research UK. And among women in their forties and fifties cancer rates have risen by more than 25 per cent...
Discovery Opens New Options For Improving Blood Transfusions
7/18/2011
Donated red blood cells lose a key feature that diminishes their lifesaving power the longer they have been stored, according to researchers at Duke University Medical Center. The finding, published Friday in the journal Critical Care Medicine, details how banked blood undergoes a change during storage that decreases its ability to transport oxygen...
Research Reveals That Significantly More Genetic Mutations Lead To Colon Cancer
7/16/2011
Researchers at UT Southwestern Medical Center say there are at least 70 genetic mutations involved in the formation of colon cancer, far more than scientists previously thought. Based on the study, published in the July 2011 Cancer Research (Priority Reports), researchers are suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously...
BioMarin Initiates Phase 1 Trial For BMN 673 In Patients With Advanced Hematological Malignancies
7/16/2011
BioMarin Pharmaceutical Inc. (Nasdaq: BMRN) announced the initiation of a Phase 1 trial for BMN 673, a poly ADP-ribose polymerase (PARP) inhibitor, for the treatment of patients with advanced hematological malignancies. A Phase 1/2 trial for BMN 673 for the treatment of patients with solid tumors was initiated in January 2011 and is ongoing...
Genes: Ready, Go!
7/16/2011
Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!"- signal to read their part of the genomic symphony...
Seattle Children's Opens New Center For Childhood Cancer Research
7/16/2011
Seattle Children's Research Institute announced the opening of the Center for Childhood Cancer Research. In tandem, Michael Jensen, MD was named as the Center's director...
Researchers Discover Why Stored Blood May Become Less Safe For Transfusion As It Ages
7/16/2011
Every two seconds, someone in the United States needs blood. In fact, more than 5 million Americans receive blood transfusions each year, according to the American Red Cross. Depending on the amount and age of the stored blood used, there is evidence that transfusion can lead to complications including infection, organ failure and death...