Tamoxifen Resistance Explained In Some Breast Cancers
7/29/2011
Using human breast cancer cells and the protein that causes fireflies to glow, a Johns Hopkins team has shed light on why some breast cancer cells become resistant to the anticancer effects of the drug tamoxifen. The key is a discovery of two genetic "dimmer switches" that apparently control how a breast cancer gene responds to the female hormone estrogen...
Mammography Results Not More Accurate Through Computer-aided Technology (CAD)
7/29/2011
A new study published by the Journal of the National Cancer Institute revealed that computer-aided detection (CAD) for analyzing and interpreting mammograms does not improve accuracy. The United States currently uses CAD technology for analyzing three out of four mammograms...
Denser Breasts Linked To Higher Cancer Risk And More Aggressive Forms Of The Disease
7/28/2011
Women whose mammograms reveal denser breasts have a greater risk of developing breast cancer, as well as more aggressive tumors compared to those whose breasts are less dense, researchers from the Harvard Medical School and Brigham and Women's Hospital, Boston, reported in the Journal of the National Cancer Institute...
Researchers Find Gene Behind Elephant Man's Disfigurement
7/28/2011
Researchers have identified a gene variant in the rare tissue and bone overgrowth disorder Proteus syndrome that may confirm the cause of the severe disfigurement suffered by "Elephant Man", a 19th century Englishman whom experts believe may have had the disease. Called AKT1, the gene may be a target for future therapies, bringing hope to patients and their families...
Link Between Breast Density And Specific Types Of Breast Cancer
7/28/2011
Women with breasts that appear dense on mammograms are at a higher risk of breast cancer and their tumors are more likely to have certain aggressive characteristics than women with less dense breasts, according to a study published online July 27 in the Journal of the National Cancer Institute...
Marshall Edwards, Inc.(Nasdaq: MSHL), an oncology company focused on the clinical development of novel therapeutics targeting cancer metabolism, announced the publication of results from a pre-clinical study of NV-128 showing activity in chemotherapy-resistant ovarian cancer stem cells...
Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) announced completion of patient enrollment in its Phase 3 registration trial of KRX-0401 (perifosine) for the treatment of refractory, advanced colorectal cancer...
Aeterna Zentaris Inc. (NASDAQ: AEZS) (TSX: AEZ) (the "Company") announced the completion of patient recruitment for the ongoing Phase 3 trial with perifosine in refractory advanced colorectal cancer. The trial, involving over 430 patients, is being conducted pursuant to a Special Protocol Assessment (SPA) with the Food and Drug Administration (FDA) and with Fast Track Designation...
Blueberries, A Cup A Day May Keep Cancer Away
7/28/2011
Blueberries are among the nutrient-rich foods being studied by UAB Comprehensive Cancer Center investigators exploring the link between disease and nutrition. Dieticians there say as little as a cup a day can help prevent cell damage linked to cancer. Why are blueberries considered healthful? They're full of antioxidants, flavonoids and other vitamins that help prevent cell damage...
Popular Mammography Tool Not Effective For Finding Invasive Breast Cancer
7/28/2011
Computer-aided detection (CAD) technology is ineffective in finding breast tumors, and appears to increase a woman's risk of being called back needlessly for additional testing following mammography, a large UC Davis study has found. The analysis of 1...