Testing Combo Therapies To Overcome Drug Resistance In Melanoma Patients
8/03/2011
About 50 to 60 percent of patients with melanoma have a mutation in the BRAF gene that drives the growth of their cancer. Most of these patients respond well to two novel agents being studied in clinical trials that inhibit the gene, with remarkable responses that are, unfortunately, almost always limited in duration...
Late-Stage Ovarian Cancer Therapy Shows Promise In Phase II Trial
8/03/2011
An experimental two-drug combination for treating late-stage ovarian cancer continues to produce strong results, leading its Indiana University researchers to actively pursue the next step, conducting a larger clinical trial to test the therapy and to see how it compares with existing treatments for ovarian cancer...
Disappearance Of Genetic Material Allows Tumor Cells To Grow
8/03/2011
Universitätsmedizin Berlin, Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, the Max-Planck-Institut für Molekulare Genetik Berlin, and four other German institutes succeeded in proving a specific gene loss in a certain human lymphoma, the genesis of which is largely unexplained to date. They investigated the so-called Sézary syndrome...
Investigation Of A New Method For The Diagnosis Of Cancer In Breast Tissue
8/03/2011
Collaboration between research, hospital and industry aimed at transferring innovative procedure into daily practice. The Paul Scherrer Institute (PSI) has developed a new breast cancer diagnostic method, and is now carrying out first tests on non-preserved human tissue in conjunction with the Kantonsspital Baden AG...
Costs Cause Many Elderly Not To Adhere To Prescribed Medication Regimen
8/02/2011
Approximately 10% of Medicare beneficiaries do not comply with their prescribed medication regimen because they simply cannot afford it, researchers from Harvard Medical School reported in the Journal of Cancer Survivorship...
Two-Drug Combination Produced Strong Results In Late Stage Ovarian Cancer Phase II Trial
8/02/2011
Researchers were surprised that late stage ovarian cancer patients responded well to an experimental carboplatin-decitabine combination therapy, given that they had become resistant to carboplatin. Indiana University researchers are eager to conduct a larger human study to test the two-drug combination with existing treatment for ovarian cancer...
Elderly In The US Find Medication Costs A Barrier To Effective Treatment
8/02/2011
As many as one in ten elderly people in the US, registered with Medicare, do not stick to their prescribed medication because it is too expensive, according to Dr. Larissa Nekhlyudov and colleagues from Harvard Medical School...
Potential For Improved Cancer Screening With New High-Speed 3-D Imaging System
8/02/2011
Researchers at the Massachusetts Institute of Technology (MIT) have developed a new imaging system that enables high-speed, three-dimensional (3-D) imaging of microscopic pre-cancerous changes in the esophagus or colon...
Predicting The Evolution Of A Patient's Tumor To Advance Highly Individualized Cancer Treatment
8/02/2011
Researchers from the University of Miami (UM) and the University of Heidelberg in Germany have developed a mathematical model to understand and predict the progress of a tumor, from its early stages to metastasis, in hopes of creating highly personalized treatment strategies for patients who have cancer. The findings are published in Nature's new online journal Scientific Reports...
The Mechanism That Determines Cell Position In The Intestinal Epithelium Discovered By Researchers
8/02/2011
How do cells know where to position themselves and where to accumulate in order to carry out their functions correctly within each organ? Researchers with the Colorectal Cancer Lab at IRB Barcelona have revealed the molecular mechanisms responsible for organizing the intestinal epithelium into distinct comportments, defined by frontiers or territories...