Immunogene Therapy Combined With Standard Treatment Is Safe For Patients With Brain Tumors
8/17/2011
A clinical trial has shown that a form of gene therapy is safe for treating a deadly form of brain cancer, even when combined with radiation therapy. The phase 1b trial was conducted at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) and at Methodist at Hospital in Houston, TX...
News From The Journals Of The American Society For Microbiology
8/17/2011
Breast Cancer Tumor Suppressor Gene Silenced by Low O2 Low oxygen can silence the BRCA1 tumor suppressor gene and contribute to the progression of cancer, according to a paper in the August 2011 issue of the journal Molecular and Cellular Biology. Silencing this particular gene is one of the steps on the malignant pathway to breast cancer...
Stem Cells Central To Pathogenesis Of Mature Lymphoid Tumors
8/17/2011
New research suggests that blood stem cells can be involved in the generation of leukemia, even when the leukemia is caused by the abnormal proliferation of mature cells. The study, published by Cell Press in the August 16th issue of the journal Cancer Cell, may guide future strategies aimed at identifying therapeutic targets for chronic lymphocytic leukemia (CLL)...
Childbearing can increase an African-American woman's likelihood of developing hormone receptor-negative breast cancer, but her risk is reduced if she breastfeeds, researchers from Boston University reported in Cancer Epidemiology, Biomarkers & Prevention. Hormone receptor-negative breast cancer is one of the hardest subtypes to treat...
Treating Resistant Prostate Cancer By Attacking Stem Cell-Like Cells
8/16/2011
Scientists from Sweden are working on a treatment which attacks stem cell-like cells in prostate cancer. The technology could be useful for prostate cancer patients who do not respond to chemotherapy or radiation therapy, the scientists informed in the journal PLoS ONE...
Higher Vitamin D Levels Linked To Higher Nonmelanoma Skin Cancer Risk
8/16/2011
People with higher levels of vitamin D appear to have a higher risk of developing NMSC (nonmelanoma skin cancer), researchers from Henry Ford Hospital, Detroit, reported in Archives of Dermatology. However, as higher UV (ultraviolet) radiation exposure general results in greater levels of vitamin D, the relationship is "complicated"...
Key Oncoprotein Discovered In Merkel Cell Carcinoma By Pittsburgh Researchers
8/16/2011
According to a study published yesterday in The Journal of Clinical Investigation, researchers at the University of Pittsburgh Cancer Institute (UPCI) have determined the oncoprotein that allows a common and usually harmless virus to change healthy cells into a rare but deadly skin cancer called Merkel Cell Carcinoma (MCC)...
Risk Of Death Reduced And Life Expectancy Increased By Just 15 Minutes Of Daily Physical Activity
8/16/2011
A study led by Dr Chi-Pang Wen, National Health Research Institutes, Taiwan, and China Medical University Hospital, and Dr Jackson Pui Man Wai, National Taiwan Sport University revealed, that only 15 minutes of daily physical activity reduces a person's risk of death by 14% and increases life expectancy by 3 years compared to inactive people. The Lancet published the study online...
Breakthrough Discovery Offers New Insight Into The Regulation Of Stem Cells And Cancer Cells
8/16/2011
Scientists at the Gladstone Institutes have gained new insight into the delicate relationship between two proteins that, when out of balance, can prevent the normal development of stem cells in the heart and may also be important in some types of cancer...
News From The Annals Of Internal Medicine: Aug. 16, 2011
8/16/2011
1. Chinese Herb Works as Well as Oseltamivir for Shortening Flu Duration The antiviral, oseltamivir has been used to reduce severity of and mortality from H1N1 influenza. In rural China, where there is limited access to medications such as oseltamivir, traditional Chinese medicine has been used to treat seasonal flu...