Knockout Of Protein Prevents Colon Tumor Formation In Mice
9/30/2011
A protein that regulates cell differentiation in normal tissue may play a different role in colon and breast cancer, activating proliferation of damaged cells, according to researchers at the University of Illinois at Chicago College of Medicine. The protein, called PTK6, is found in normal skin and gut cells -- and in cancerous, but not normal, breast tissue...
Kimmel Cancer Center At Jefferson Celebrates 20 Years Of Patient Care And Cancer Discovery
9/30/2011
From October forward, the Kimmel Cancer Center at Jefferson (KCC), a National Cancer Institute-designated cancer center, is celebrating 20 years of service to the community and the groundbreaking cancer research from the scientists and physicians who've provided an invaluable contribution to medical science and healthcare...
St. Jude Children's Research Hospital Discovery Aided Quest For Adult Cancer Drug
9/30/2011
A drug recently approved by the U.S. Food and Drug Administration for treatment of an adult cancer targets a malfunctioning gene discovered more than a decade earlier at St. Jude Children's Research Hospital. The story highlights how scientific findings from St. Jude can be translated into therapies and tests that in addition to helping children, also help adults...
Impediment To Some Cancer Immunotherapy Involves Free Radical Peroxynitrite
9/30/2011
Researchers at the Moffitt Cancer Center in Tampa, Fla., and colleagues have found that tumor cell resistance to a specific cancer immunotherapy designed to kill cancer cells can be blamed on a mechanism that involves the production of a free radical peroxynitrite (PNT) that causes resistance to therapeutic cancer-killing cells...
Using Immune System To Fight Metastatic Melanoma
9/30/2011
A new cancer research program at Loyola University Chicago Stritch School of Medicine will develop therapies designed to turn patients' own immune systems into potent weapons against cancer. The first project is an immune system therapy for metastatic melanoma. A clinical trial, expected to begin early next year, will be the only one of its kind in the Midwest...
Bowel Cancer Prevention Screening In Men Advised From The Age Of 45 Onwards
9/30/2011
Each year, around 5,000 people die from colorectal cancer in Austria, with the mortality rate being just under 50 per cent. A screening colonoscopy (bowel imaging) is recommended in Austria for people who turn 50, regardless of their gender...
A recent, large-scale study on cat intestinal cancer has provided new insight into a common pet disease and its causes; the findings could ultimately benefit humans. "We are looking for patterns of cancer development in animals, so we can find common risk factors," said Kim Selting, associate teaching professor of oncology at the MU College of Veterinary Medicine...
A Step Closer To Correcting Sickle Cell Disease With Stem Cells
9/30/2011
Using a patient's own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene...
Gene May Be Good Target For Tough-To-Kill Prostate Cancer Cells
9/30/2011
Purdue University scientists believe they have found an effective target for killing late-stage, metastatic prostate cancer cells. Xiaoqi Liu, an assistant professor of biochemistry and member of Purdue's Center for Cancer Research, and graduate student Shawn Liu are focusing on the function of a gene called Polo-like kinase (Plk1), a critical regulator of the cell cycle...
Permanent Nerve Damage May Be Side-Effect Of Popular Colorectal Cancer Drug
9/30/2011
Oxaliplatin, a platinum-based anticancer drug that's made enormous headway in recent years against colorectal cancer, appears to cause nerve damage that may be permanent and worsens even months after treatment ends...