Details Of Alternative Splicing Circuitry That Promotes Cancer's Warburg Effect Revealed By Study
11/04/2011
Cancer cells maintain their life-style of extremely rapid growth and proliferation thanks to an enzyme called PK-M2 (pyruvate kinase M2) that alters the cells' ability to metabolize glucose - a phenomenon known as the Warburg effect. Professor Adrian Krainer, Ph.D...
Effectiveness And Safety Of New Treatment For Hemophilia Confirmed By Tulane-Led Study
11/04/2011
An international research team led by Dr. Cindy Leissinger of Tulane University School of Medicine, along with Dr. Alessandro Gringeri from the University of Milan, has found that a drug commonly used to treat bleeding events in people with a type of severe hemophilia can also be used to prevent such events from happening in the first place...
Experimental Drug Shows Great Results On Prostate Cancer
11/04/2011
An experimental drug known as MDV3100 made by Medivation Inc. has improved survival rates for men with metastatic castration-resistant prostate cancer. Those on MDV3100 by Medivation outlived those on a placebo by an average of 4.8 months, in a phase 3 trial. The manufacturer Medivation Inc...
Use Of New Catalyst To Synthesize Two Potent Anti-Cancer Molecules
11/04/2011
Research carried out at Boston College, in collaboration with scientists at MIT and the University of Oxford, has led to the development of an efficient and highly selective catalyst for ring-closing olefin metathesis, one of the most widely used reactions in chemical synthesis, the team reports in this week's issue of the journal Nature...
Tactic To Delay Age-Related Disorders Discovered By Mayo Researchers
11/04/2011
Researchers at Mayo Clinic (http://www.mayoclinic.org) have shown that eliminating cells that accumulate with age could prevent or delay the onset of age-related disorders and disabilities. The study, performed in mouse models, provides the first evidence that these "deadbeat" cells could contribute to aging and suggests a way to help people stay healthier as they age...
Mayo Clinic researchers have discovered why measles, perhaps the most contagious viral disease in the world, spreads so quickly. The virus emerges in the trachea of its host, provoking a cough that fills the air with particles ready to infect the next host. The findings may also help in the fight against ovarian, breast and lung cancers...
Potential Treatment For Sickle Cell Disease
11/04/2011
A University of Michigan Health System laboratory study reveals a key trigger for producing normal red blood cells that could lead to a new treatment for those with sickle cell disease...
Experimental Drug Shows Great Results On Prostate Cancer
11/04/2011
An experimental drug known as MDV3100 made by Medivation Inc. has improved survival rates for men with metastatic castration-resistant prostate cancer. Those on MDV3100 by Medivation outlived those on a placebo by an average of 4.8 months, in a phase 3 trial. The manufacturer Medivation Inc...
Cetuximab Extends Lifespan Of Lung Cancer Patients With High EGFR Expression
11/03/2011
A study published Online First in The Lancet Oncology reveals that patients who suffer from the most common form of lung cancer and whose tumors express high levels of epidermal growth factor receptor (EGFR) tend to benefit more from being treated with cetuximab and have a longer life-expectancy compared with those given chemotherapy alone...
Cetuximab Extends Lifespan Of Lung Cancer Patients With High EGFR Expression
11/03/2011
A study published Online First in The Lancet Oncology reveals that patients who suffer from the most common form of lung cancer and whose tumors express high levels of epidermal growth factor receptor (EGFR) tend to benefit more from being treated with cetuximab and have a longer life-expectancy compared with those given chemotherapy alone...