Little-Studied Cellular Mechanism Elevated To Potential Drug Target
12/13/2011
For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes from cell metabolism to programmed cell death...
Study Points To Novel Way To Improve Outcomes From Umbilical Cord Blood Transplants
12/13/2011
A new method to boost the number of immune cells in umbilical cord blood prior to cord blood transplants for cancer patients appears to lead to a quicker rebuilding of a new immune system in the patient's body than with a conventional cord blood transplant procedure, according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be pr...
Adults With Hemophilia B Benefit From Gene Therapy
12/13/2011
Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U.K...
Nab-Paclitaxel Beats Docetaxel As First-Line Treatment For Metastatic Breast Cancer
12/12/2011
Nab-paclitaxel (Abraxane for Injectable Suspension), at a dose of 150 mg/m2 weekly, improves overall survival (OS) to a much greater degree than conventional taxane monotherapy in women with previously untreated metastatic breast cancer (MBC), according to results of a phase II study released at the 34th Annual San Antonio Breast Cancer symposium (SABCS)...
Cancer Screening In Older Patients Very Common
12/12/2011
U.S. Preventive Services Task Force guidelines recommend against routine cancer screening, especially for breast, cervical, colorectal and prostate cancer, but adults 75 and older are still receiving regular cancer screenings...
Prostate Cancer - Cardiovascular Risks Linked To Androgen Suppression Therapy Ignored
12/12/2011
According to specialists' warnings published in Heart, it has been established that androgen suppression therapy (AST) drugs, that suppress testosterone production for the treatment of prostate cancer, can lead to complications in form of stroke and heart disease, yet standard management of the disease ignores this risk...
Screening Finds More Left Sided Bowel Cancers
12/12/2011
Bowel cancer is responsible for 16,000 deaths annually in the UK alone. Bowel cancer is the second leading cause of death in the UK and Europe after lung cancer. The chances of survival are only 50% in the UK, and even remarkably lower in other similar countries...
More Negatives Linked To Breast Screening Than Positives? Possibly
12/12/2011
'Introducing breast cancer screening in the UK may have caused more harm than good', says a new study published on bmj.com that supports the claim...
Stop-Start Low-Carb Diets More Effective Than Standard Dieting
12/12/2011
Recent findings presented by researchers at Genesis Prevention Center at University Hospital in South Manchester, England, at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium, have demonstrated that an intermittent, low-carbohydrate diet is preferable to a standard and daily calorie-restricted diet to reduce weight and lower blood levels of insulin...
PSA Testing, Combined With Other Relevant Patient Data Can Reduce Unnecessary Prostate Biopsies
12/12/2011
A study published online by the journal Cancer reveals that up to one-quarter of men could avoid biopsies and their associated risks with prostate cancer screening that combines an adjusted blood test with other factors including, the patient's family history, overall weight as well as the size of the gland. According to the team led by Martin G...