Roche (SIX: RO, ROG; OTCQX: RHHBY), announced that the Committee for Medicinal Products for Human Use (CHMP) has recommended that Zelboraf be granted full marketing authorization as a monotherapy for the treatment of adult patients with BRAF V600 mutation-positive unresectable or metastatic melanoma...
Tissue Structure Delays Cancer Development
12/20/2011
Cancer growth normally follows a lengthy period of development. Over the course of time, genetic mutations often accumulate in cells, leading first to pre-cancerous conditions and ultimately to tumour growth...
Sunless Tanning Product Users Sunbathe Less
12/20/2011
Young adult females who use tanning lotions and other sunless tanning products tend to sunbathe and use tanning salons less than other women of their age, researchers from Emory University School of Medicine, Atlanta, Georgia, reported in Archives of Dermatology. They added that the more a woman used sunless tanning products, the less she tended to sunbathe or use tanning salons...
Pediatric Cancer Survivors May Develop Heart Problems Later
12/20/2011
Will a drug used to treat childhood acute lymphoblastic leukemia and other pediatric cancers cause heart problems later in life? UB associate professor of pharmaceutical sciences, Javier G. Blanco, PhD, who sees his work as a bridge between research and clinical practice, has focused recent efforts on trying to answer this question...
Clues That Could Improve Therapy Revealed By First Comprehensive DNA Study Of Mast Cell Leukemia
12/20/2011
Cancer researchers at Cold Spring Harbor Laboratory (CSHL) have carried out the first comprehensive study of the changes seen in the DNA of a patient with mast cell leukemia (MCL), an extremely aggressive subtype of acute myeloid leukemia (AML) with a very poor prognosis...
Potential To Double The Efficacy Of Radiation Therapy
12/20/2011
Scientists may have a way to double the efficacy and reduce the side effects of radiation therapy. Georgia Health Sciences University scientists have devised a way to reduce lung cancer cells' ability to repair the lethal double-strand DNA breaks caused by radiation therapy. "Radiation is a great therapy - the problem is the side effects," said Dr. William S...
Fetal Exposure To Carcinogens Leading To Cancer Depends On Dose, Timing
12/20/2011
The cancer-causing potential of fetal exposure to carcinogens can vary substantially, a recent study suggests, causing different types of problems much later in life depending on the stage of pregnancy when the fetus is exposed. The research sheds further light on the way in which toxic damage early in life can later manifest themselves as cancer, due to "epigenetic" changes in cells...
Phase 2 Trial Finds Spread Of Nasopharyngeal Carcinoma Is Reduced By Bevacizumab
12/20/2011
The trial conducted by the Radiation Therapy Oncology Group (RTOG) shows the feasibility to deliver bevacizumab to the current chemoradiation standard without any apparent increased adverse side effects...
Advantages And Motivations Uncertain Behind Use Of Brachytherapy For Breast Cancer Radiotherapy
12/20/2011
Accelerated partial breast irradiation using brachytherapy (APBIb) for the treatment of breast cancer has been rapidly increasing over the last several years in the U.S. as an alternative to standard whole-breast irradiation (WBI), according to a study published in the Journal of the National Cancer Institute...
No Brakes On Breast Cancer Cells
12/20/2011
MicroRNAs or miRNAs are tiny RNA molecules that have only about 20 nucleotides and do not code for proteins. They regulate many important processes in cells by binding to target messenger RNAs - the instructions for protein production - thus blocking production of the respective protein. In cancer, the production of some miRNAs is often reduced or amplified...