Genetic Composition Of Multicentric Lung Tumors Appears To Be Similar
1/10/2012
Multicentric carcinogenesis with the same genetic mutation appears to occur in lung adenocarcinoma, according to data presented at the AACR-IASLC Joint Conference on Molecular Origins of Lung Cancer: Biology, Therapy and Personalized Medicine, held Jan. 8-11, 2012...
Potential Genetic Origins, Pathways Of Lung Cancer In Never-Smokers, Mapped By Researchers
1/10/2012
Researchers have begun to identify which mutations and pathway changes lead to lung cancer in never-smokers - a first step in developing potential therapeutic targets. Never-smokers (defined as an individual who smoked fewer than 100 cigarettes in his or her lifetime) are estimated to account for 10 percent of lung cancer cases...
Lung Cancer Prevention Potential For Estrogen-Targeting Drug Combo
1/10/2012
A combination of drugs that target estrogen production significantly reduced the number of tobacco carcinogen-induced lung tumors in mice, according to results from a preclinical study. "Antiestrogens have been shown to prevent breast cancer in some women," said Jill M. Siegfried, Ph.D...
Indication Of Considerable Added Benefit From Abiraterone In Certain Prostate Cancer Patients
1/10/2012
Advantages for men with metastatic hormone-refractory prostate cancer who are no longer eligible for docetaxel therapy Abiraterone (trade name: Zytiga®) has been approved since September 2011 for men with metastatic prostate cancer that is no longer responsive to hormone therapy and progresses further during or after therapy with the cytostatic drug docetaxel...
Smokers Taking Statins May Be At Increased Risk Of Interstitial Lung Abnormalities
1/10/2012
Use of statins may influence susceptibility to or the progression of interstitial lung disease (ILD) in smokers, according to a new study...
Researchers Find Malignancy-Risk Gene Signature For Early-Stage Non-Small Cell Lung Cancer
1/10/2012
A malignancy-risk gene signature developed for breast cancer has been found to have predictive and prognostic value for patients with early stage non-small cell lung cancer. The advancement was made by researchers at Moffitt Cancer Center in Tampa, Fla., who published their study results in a recent issue of the Journal of the National Cancer Institute...
Newcastle Scientists Find Genetic Key To Why Some Cancer Patients Don't Respond To Treatment
1/09/2012
In a study funded by the charity Leukemia & Lymphoma Research published in the leukemia journal Blood in January, scientists from Newcastle University have discovered a gene variation that occurs in 20% of the population, which can have a substantial effect on treatment responses in patients with a rare type of blood cancer...
Lithocholic Acid Kills Cancer Cells But Not Healthy Cells
1/09/2012
The abilities of an acid that is naturally produced in the liver during digestion, called Lithocholic acid (LCA) have seriously been underestimated until now. According to a study led by Concordia University published in Oncotarget, LCA can kill several types of cancer cells, including those found in some brain tumors and breast cancer...
Test All Hospitalized Patients For Blood Glucose Levels, Experts Say
1/09/2012
Hyperglycemia, or high blood sugar (glucose) levels, is a common, serious and expensive health care problem in hospitalized patients that is linked to an increased risk of health complications and mortality. It can also affect non-diabetic hospitalized patients. According to observational studies, 32 to 38% of patients in community hospitals suffer from hyperglycemia...
Yearly Prostate Cancer Screening Does Not Lower Total Number Of Deaths
1/09/2012
Mass prostate cancer screenings do not lower total number of deaths from prostate cancer, researchers from Washington University School of Medicine at St. Louis reported in the Journal of the National Cancer Institute. They added that mass routine screenings do not even reduce numbers of deaths among males in their fifties and sixties, as well as patients with underlying health conditions...