Tapping The Body's Own Defenses, Researchers Look To Cutting-Edge Gene Therapy For Bladder Cancer
1/12/2012
Bladder cancer, most frequently caused by smoking and exposure to carcinogens in the workplace, is one of the top 10 most common forms of cancer in men and women in the U.S. More than 70 percent of bladder cancers are diagnosed in stage T1 or less and have not invaded the muscle layer...
Major Advance In Understanding The Regulation Of An Important Cancer Target
1/12/2012
Scientists at the University of Leicester have opened up a whole new approach to the therapeutic intervention for a family of anti-cancer drug targets, thanks to a completely new and unexpected finding...
Siblings Of Children With Cancer Helped By New Educational Program
1/12/2012
Having a brother or sister with newly diagnosed cancer can be a distressing and difficult time for a child. While most children eventually cope, there can be a period of adjustment when their school work and social functioning suffer...
Study Reveals Need For Improvements In Decision-Making Process For Breast Cancer Surgery Patients
1/12/2012
According to the results of a new study published in the January 2012 issue of the Journal of the American College of Surgeons, many early-stage breast cancer survivors lacked knowledge about their disease and were not meaningfully involved in treatment discussions or asked their preferences regarding the approach to treatment...
Nanotechnology Researchers Develop New Strategy To Deliver Chemotherapy To Prostate Cancer Cells
1/11/2012
Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy "bait" is a greater challenge...
A new study from SUNY Downstate Medical Center in Brooklyn, New York, shows that MAL3-101, a recently developed inhibitor of the heat shock protein 70 (Hsp70), appears to have potent anti-tumor effects on multiple myeloma, a bone marrow cancer. Despite aggressive modes of treatments, myeloma ultimately remains incurable. The disease has a high incidence in the communities served by SUNY Downstate...
As Monotherapy And In Combinations, Ganetespib Showed Activity In KRAS-Mutant NSCLC
1/11/2012
The investigational drug ganetespib, a synthetic second-generation Hsp90 inhibitor, slowed the growth of cancer cells taken from non-small cell lung cancer tumors with a mutation in the KRAS gene. The drug was even more active when combined with traditional lung cancer treatments and other investigational targeted therapies, according to preclinical study data. David A. Proia, Ph.D...
Identification Of Precancer Markers In Airway Epithelium Cells Of Healthy Smokers
1/11/2012
Smoking may be associated with the development of molecular features of cancer in the large airway epithelium. In the small airway epithelium, molecular cancerization is associated with development of chronic obstructive pulmonary disease, according to recent data...
Annual Bleeding Events And Frequency Of Infusions Reduced By Preventive Hemophilia A Treatment
1/11/2012
A Rush University Medical Center led international research team has announced that a treatment to prevent bleeding episodes in children with hemophilia A also is effective for adolescents and adults. The preventive therapy will "optimize care for hemophilia patients of all ages by stopping unexpected bleeding events that can have a detrimental impact on the lives of patients," said Dr...
Anxiety, Pain During Prostate Biopsies Eased By Headphone Music
1/11/2012
Tuning in to tune out may be just what's needed for men undergoing a prostate biopsy, according to researchers at the Duke Cancer Institute. The Duke team found that noise-cancelling headphones playing a classical melody may reduce the pain and anxiety of the often uncomfortable procedure...