New Drug For Advanced Colorectal Cancer Shows Promise In Trial
1/18/2012
An experimental drug for advanced colorectal cancer that available treatments have failed to halt, has shown promise in a clinical trial, says Bayer HealthCare, the company that makes it. The results of the phase III trial show that compared to placebo, regorafenib slowed tumor growth and extended survival...
Researchers Elucidate Mechanism By Which Immune Cells Destroy Cancer Cells
1/18/2012
In the treatment of large tumors, how effective is adoptive T cell therapy in comparison to drug-based cancer treatment? To answer this question, Dr...
Plasmacytoid DCs: Tumor-killing Immune Cells
1/18/2012
Some skin cancers, in particular basal cell carcinoma, can be successfully treated with a prescription cream containing the compound imiquimod. The antitumor effect of imiquimod is multifactorial. One of the more complex aspects of imiquimod's antitumor effects is its ability to modify the immune response...
Study Published On Novel Treatment For Skin Lymphoma
1/18/2012
Promising findings on a novel combination treatment approach for a chronic type of skin lymphoma are published in JAMA's Archives of Dermatology by clinical researchers from Seidman Cancer Center at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine...
New Achilles Heel In Acute Myeloid Leukaemia Identified By Cell Death Researchers
1/18/2012
Melbourne researchers have discovered that acute myeloid leukaemia (AML), an aggressive blood cancer with poor prognosis, may be susceptible to medications that target a protein called Mcl-1...
Esophageal Cancer May Be Caused By Migration Of Cancer-Causing Stomach Cells
1/18/2012
A new study is providing clues that may answer a decades-old question about the cells that give rise to a particularly lethal form of esophageal cancer...
Paradoxical Discovery Finds That A Group Of Cells Known As Pericytes Help Prevent Metastasis
1/18/2012
A new study finds that a group of little-explored cells in the tumor microenvironment likely serve as important gatekeepers against cancer progression and metastasis...
News From The Journal Of Clinical Investigation: Jan. 17, 2012
1/18/2012
VIROLOGY: How to prevent hepatitis B virus reproducing Infection with hepatitis B virus (HBV) is a major health problem worldwide, despite the fact that a highly effective preventative vaccine exists. A modified form of the immune molecule IFN-alpha is commonly used to treat individuals infected with HBV...
Plasmacytoid DCs: Tumor-killing Immune Cells
1/18/2012
Some skin cancers, in particular basal cell carcinoma, can be successfully treated with a prescription cream containing the compound imiquimod. The antitumor effect of imiquimod is multifactorial. One of the more complex aspects of imiquimod's antitumor effects is its ability to modify the immune response...
Declines In Melanoma Deaths Limited To The Most Educated
1/18/2012
A new study from the American Cancer Society finds recent declines in melanoma mortality rates in non-Hispanic Whites in the U.S. mainly reflect declines in those with the highest level of education, and reveals a widening disparity in melanoma mortality rates by education...