Breast Cancers And Leukemias Slowed By A Single Therapy
1/24/2012
Targeting a single protein can help fight both breast cancers and leukemias, according to two reports published online in the Journal of Experimental Medicine. The single protein is HSP90, which acts as a chaperone to protect other proteins in the cell...
Cervical Cancer Screening Via Self-Collection
1/24/2012
Human papillomavirus (HPV) testing of self-collected specimens may be a more effective way to screen for cervical cancer in low-resource settings compared to visual inspection with acetic acid (VIA) and liquid-based cytology (LBC), according to a study published in the Journal of the National Cancer Institute...
Quality of life in younger patients treated for breast cancer is seriously compromised and these women suffer from severe psychological distress, infertility, premature menopause, a decrease in physical activity and weight gain, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center...
The Genome And The Timing Of Menopause
1/24/2012
An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause. These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease...
Cervical Cancer Screening Via Self-Collection
1/24/2012
Human papillomavirus (HPV) testing of self-collected specimens may be a more effective way to screen for cervical cancer in low-resource settings compared to visual inspection with acetic acid (VIA) and liquid-based cytology (LBC), according to a study published in the Journal of the National Cancer Institute...
Quality Of Life Issues For Patients With Chronic Myeloid Leukemia
1/24/2012
Although significant progress has been made in treating chronic myeloid leukemia, the disease cannot yet be eliminated in all patients, and that challenge must be addressed, states a commentary in CMAJ (Canadian Medical Association Journal).). Likening the journey to find a cure for chronic myeloid leukemia as a marathon, cancer expert Dr...
In Cancer Metastasis, DGK-Alpha Helps Cancer Cells Gain Traction And Mobilize
1/24/2012
Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins. Adhesive integrin proteins continually cycle to and from the cell surface...
The expression of p53 and Mdm2 is closely related. In an article published this week in the Cancer Cell review, Robin Fahraeus and his collaborators from Inserm Unit 940 ("Therapeutic Targets for Cancer"), demonstrate that cellular response to DNA damage requires involvement from the protein kinase ATM so that Mdm2 can positively or negatively control protein p53...
How Immune Cells Move Against Invaders
1/24/2012
UCSF scientists have discovered the unexpected way in which a key cell of the immune system prepares for battle. The finding, they said, offers insight into the processes that take place within these cells and could lead to strategies for treating conditions from spinal cord injury to cancer. The research focused on the neutrophil, the most common type of white blood cell...
'Pulverized' Chromosomes Linked To Cancer?
1/24/2012
They are the Robinson Crusoes of the intracellular world - lone chromosomes, whole and hardy, stranded outside the nucleus where their fellow chromosomes reside. Such castaways, each confined to its own "micronucleus," are often found in cancer cells, but scientists haven't known what role, if any, they play in the cancer process...