New Prostate Cancer Drug Target Identified
2/07/2012

Research led by Wanguo Liu, PhD, Associate Professor of Genetics at LSU Health Sciences Center New Orleans, has identified a new protein critical to the development and growth of prostate cancer. The findings are published online in the Early Edition of Proceedings of the National Academy of Sciences, available the week of February 6, 2012. Dr...

Increased Risk Of Fatal Side Effects From 3 'Targeted' Cancer Drugs
2/07/2012

Treatment with three relatively new "targeted" cancer drugs has been linked to a slightly elevated chance of fatal side effects, according to a new analysis led by scientists at Dana-Farber Cancer Institute. They added that the risk remains low, but should be taken into account by physicians and patients. The incidence of fatal complications was 1...

More Accurate Diagnosis Of Genetic Mutations Expected Using New Virtual Tool
2/07/2012

DNA sequencing to detect genetic mutations can aid in the diagnosis and selection of treatment for cancer. Current methods of testing DNA samples, Sanger sequencing and pyrosequencing, occasionally produce complex results that can be difficult or impossible to interpret...

A Particular Breast Cancer Subtype May Respond To Drugs Targeting Chromosomal Instability
2/07/2012

Another layer in breast cancer genetics has been peeled back. A team of researchers at Jefferson's Kimmel Cancer Center (KCC) led by Richard G. Pestell, M.D., PhD...

New Prostate Cancer Drug Target Identified
2/07/2012

Research led by Wanguo Liu, PhD, Associate Professor of Genetics at LSU Health Sciences Center New Orleans, has identified a new protein critical to the development and growth of prostate cancer. The findings are published online in the Early Edition of Proceedings of the National Academy of Sciences, available the week of February 6, 2012. Dr...

Study Identifies Molecular Switch That Allows Melanoma To Resist Therapy
2/07/2012

The National Cancer Institute (NCI) estimates that as many as one in 51 men and women will be diagnosed with melanoma - the deadliest form of skin cancer - at some point during their lifetimes. A research team led by Ze'ev Ronai, Ph.D...

Breakthroughs Demonstrate Importance Of Targeted Therapies For Lung Cancer
2/07/2012

Different kinds of lung cancer behave in different ways, suggesting they are fundamentally different diseases. According to a University of Colorado Cancer Center study published in Cancer, the official journal of the American Cancer Society, different subgroups of non-small cell lung cancer (NSCLC) show distinct patterns of spread in the body...

Reviewing Ways To Balance The Benefits Of Oxaliplatin With Its Side Effects When Treating Colon Cancer
2/07/2012

The drug oxaliplatin is a major reason the prognosis for metastatic colon cancer has gone from an expected survival of several months to a couple years. Unfortunately, the drug can also carry with it debilitating neurological side effects, which generally start as the sensation of pins and needles in fingers and toes and can leave patients unable to walk or dress independently...