Early Changes Leading To Breast Tumors Revealed By Spectroscopic Imaging
3/08/2012
Purdue University researchers have created a new imaging technology that reveals subtle changes in breast tissue, representing a potential tool to determine a woman's risk of developing breast cancer and to study ways of preventing the disease...
Blocking Receptor Protein Prevents The Development Of Breast Cancer Metastases In Mice
3/08/2012
In particularly aggressive forms of breast cancer, cancer cells can settle in other organs and form metastases there. Once such metastases form, complete recovery is rare. Consequently, it is enormously important to prevent the metastasisation of the breast cancer cells. The success, however, achieved by using existing forms of therapy is limited...
Advanced Melanoma: Using Patients' Own Anti-Tumor Cells Holds Treatment Promise
3/08/2012
Results of a small trial published online on 5 March in the Proceedings of the National Academy of Sciences, where patients with progressive metastatic melanoma were treated with billions of lab-grown clones of the their own anti-tumor cells, are raising hopes that a treatment can be developed to knock back the advanced form of this most dangerous skin cancer...
Understudied, Unwelcome Side Of Cancer Treatment Highlighted By Report
3/08/2012
The number of cancer survivors in the United States has tripled since 1971 and yet gains in survival have come at the price of second malignancies and cardiovascular disease, according to a long-awaited report by a national scientific committee chaired by Lois B. Travis, M.D., Sc.D., of the University of Rochester Medical Center...
Surprising Discovery In Mouse Model Reveals That An Anti-Cancer Gene Also Fights Obesity
3/08/2012
This result, obtained after five years' research, is published in leading journal Cell Metabolism. The authors, led by Manuel Serrano (CNIO), believe it will open the door to new therapeutic options not only against cancer, but against obesity and even the ageing process...
Cancer Vaccines And The Challenges They Present
3/08/2012
The first therapeutic cancer vaccine has now been approved by the FDA, and a diverse range of therapeutic cancer vaccines directed against a spectrum of tumor-associated antigens are currently being evaluated in clinical trials, according to a review published in the Journal of the National Cancer Institute...
How Protein Machinery Binds And Wraps DNA To Start Replication
3/08/2012
Before any cell - healthy or cancerous - can divide, it has to replicate its DNA. So scientists who want to know how normal cells work - and perhaps how to stop abnormal ones - are keen to understand this process. As a step toward that goal, scientists at the U.S...
Footloose And Cancer Free - Mice With Pten
3/08/2012
In a perfect world, we could eat to our heart's content without sacrificing our health and good looks, and now it appears that maybe we can. Mice with an extra dose of a known anti-cancer gene lose weight even as their appetites grow...
CYP2D6 Genotype Not Found To Predict Tamoxifen Benefit In Breast Cancer
3/08/2012
Two studies published in the Journal of the National Cancer Institute provide insights about the CYP2D6 genotype in postmenopausal breast cancer patients and represent a major step forward in understanding the usefulness of CYP2D6 testing for deciding whether or not a patient should receive adjuvant tamoxifen for treatment of early-stage breast cancer...
Embryonic Development Protein Active In Cancer Growth
3/08/2012
A team of scientists at the University of California, San Diego Moores Cancer Center has identified a novel protein expressed by breast cancer cells - but not normal adult tissues - that could provide a new target for future anti-cancer drugs and treatments. Led by Thomas J...