Plerixafor Makes Leukemia More Vulnerable To Chemo
3/21/2012
Doctors at Washington University School of Medicine in St. Louis have shown that a new drug makes chemotherapy more effective in treating acute myeloid leukemia, a cancer of the white blood cells. Instead of attacking these cells directly, the drug helps drive them out of the bone marrow and into the bloodstream, where they are more vulnerable to chemotherapy...
Combining RNA Interference With Tyrosine Kinase Inhibitors Or Cetuximab Enhances Lung Cancer Therapy
3/21/2012
Non-small cell lung cancer (NSCLC), the most common form of lung cancer, is usually treated with surgery and chemotherapy. However, a small group of patients can also be helped by treatment with tyrosine kinase inhibitors (TKI)...
Using Molecular Analysis To Identify Specific Cancers
3/21/2012
Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report they have discovered a method to identify cancer-causing rearrangements of genetic material called chromosomal translocations quickly, accurately, and inexpensively. A description of the method and the research results appear online in this month's issue of the EMBO Molecular Medicine journal...
Two Cancer-Promoting Pathways Linked In Esophageal Cancer
3/21/2012
Identification of a non-traditional pathway for spiriting a cancer-promoting protein into the cell nucleus points to a possible combination therapy for esophageal cancer and indicates a mechanism of resistance for new drugs that attack the Hedgehog pathway...
For the past 40 years, radiation has been the most effective method for treating deadly brain tumors called glioblastomas. But, although the targeting technology has been refined, beams of radiation still must pass through healthy brain tissue to reach the tumor, and patients can only tolerate small amounts before developing serious side effects...
Researchers Building Melanoma Vaccine To Combat Skin Cancer
3/21/2012
Mayo Clinic researchers have trained mouse immune systems to eradicate skin cancer from within, using a genetic combination of human DNA from melanoma cells and a cousin of the rabies virus. The strategy, called cancer immunotherapy, uses a genetically engineered version of the vesicular stomatitis virus to deliver a broad spectrum of genes derived from melanoma cancer cells directly into tumors...
Novel Therapy Discovered For Crohn's Disease
3/21/2012
The Nutritional Immunology and Molecular Medicine Laboratory (NIMML) research team at Virginia Tech has discovered important new information on the efficacy of conjugated linoleic acid (CLA) in treating Crohn's disease, a form of inflammatory bowel disease (IBD). CLA is a naturally occurring acid found in meat and dairy products known for its anti-cancer and immune modulatory properties...
New Method To Test A Tumor's Resistance To An Experimental Therapy
3/21/2012
Drug resistance is a serious problem for cancer patients - over time, a therapy that was once providing some benefit simply stops working. Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) recently discovered how cancer cells develop resistance to a drug called MLN4924...
Publication Of Cytori Breast Reconstruction Cell Therapy Trial Results
3/21/2012
Cytori Therapeutics (NASDAQ: CYTX) has announced the publication of RESTORE-2 trial results in the peer-reviewed European Journal of Surgical Oncology. RESTORE-2 is a 71 patient multi-center, prospective clinical trial using autologous adipose-derived regenerative cell (ADRC)-enriched fat grafting for reconstruction of the breast after cancer surgery...
Improved Understanding Of Blood Clotting
3/21/2012
How and when our blood clots is one of those incredibly complex and important processes in our body that we rarely think about. If your blood doesn't clot and you cut yourself, you could bleed to death, if your blood clots too much, you could be in line for a heart attack or stroke. Dr...