Potential To Predict And Detect Breast Cancer With The Help Of 'Obscurins' In Breast Tissue
3/23/2012
A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the University of Maryland, explain how proteins, called "obscurins," once believed to only be in muscle cells, act as "tumor suppressor genes" in the breast...
Circulating Tumour Cells Predict Chances Of Survival And Can Help Target Breast Cancer Treatment
3/23/2012
Detecting the presence of circulating tumour cells (CTCs) in the blood of women with early breast cancer after surgery but before the start of chemotherapy can provide useful information about their chances of surviving the disease. CTCs are cancer cells which are detectable in patients with a solid tumour and their value in the prognosis of metastatic breast cancer has been known for a few years...
Medical Staff Confuse Women With Ductal Carcinoma In Situ: Is It Breast Cancer, Or Not?
3/23/2012
Women diagnosed with ductal carcinoma in situ (DCIS) need clear communication and tailored support to enable them to understand this complex breast condition, which has divided the medical profession when it comes to its perception and prognosis. That is the key finding of a study published in the April issue of the Journal of Advanced Nursing...
Vemurafenib Effective For Some Metastatic Melanoma Patients
3/22/2012
Results from a phase II multi-center clinical trial involving 132 patients with previously treated BRAF V600-mutant metastatic melanoma, indicate that vemurafenib (PLX4032) - an oral BRAF inhibitor - offered a high rate of response in some patients. According to the researchers from the U.S. and Australia, including researchers at Moffitt Cancer Center in Tampa, Fla...
New Cancer Test Is Cheap, Accurate And Fast
3/22/2012
This month's issue of the online EMBO Molecular Medicine Journal reports that researchers from the Huntsman Cancer Institute (HCI) at the University of Utah have discovered a rapid, precise and cost-efficient way to identify cancer-causing rearrangements of genetic material, called chromosomal translocations that occur in the tumor cells of many cancers...
Potential Strategy Aims To Stimulate The Immune System To Defeat Cancers
3/22/2012
A new finding in basic science should trigger a "change in thinking" about how cancer drugs might be developed and tested for maximum effectiveness, says Louis M. Weiner, M.D...
Significant Numbers Of Lives Saved By Breast Cancer Screening And Better Treatment
3/22/2012
A Dutch study of the effectiveness of breast cancer screening shows that, even with improved treatments for the disease, population-based mammography programmes still save a significant number of lives...
Women With A Family History Of Breast Cancer But No Genetic Predisposition
3/22/2012
Adding magnetic resonance imaging (MRI) to standard breast cancer screening approaches is expensive, though it could be cost effective for a group of women who may not have inherited the breast cancer susceptibility genes, but who have a familial risk of developing the disease. This is the conclusion of research presented at the eighth European Breast Cancer Conference (EBCC-8)...
Results from one of the longest-running national breast cancer screening programmes have shown that it has contributed to a drop in deaths from the disease, that any harm caused by the screening, such as false positives and over-diagnosis, has been limited, and that the costs have been reasonable...
Dense Breasts Can Nearly Double The Risk Of Breast Cancer Recurrence
3/22/2012
Women aged 50 and over with breasts that have a high percentage of dense tissue are at greater risk of their breast cancer recurring, according to Swedish research presented at the eighth European Breast Cancer Conference (EBCC-8) in Vienna...