Predicting Chemotherapy Side Effects Through Understanding Of Individual Genetic Variation
3/26/2012
The largest study ever on the effect of genetic variability on the toxicity of chemotherapy in breast cancer shows that it is possible to predict which patients are most likely to suffer serious side effects, a researchertold the 8th European Breast Cancer Conference (EBCC-8). Dr...
Daily Aspirin - More Benefit Than Risk?
3/25/2012
Many people take a low dose of aspirin every day to lower their risk of a further heart attack or stroke, or if they have a high risk of either. While the anticipated benefit is a lower chance of vascular disease, taking daily aspirin is not without danger: for instance it raises the risk of internal bleeding...
Thromboembolic Events Are Uncommon Following Ankle Fracture Surgery
3/25/2012
Thromboembolic events - such as deep vein thrombosis (DVT), blood clots developing in the extremities; or pulmonary embolism (PE), a complication that causes a blood clot to move to the lungs - can occur following musculoskeletal injury and related surgery, and are potentially life threatening...
Worm Model Of Back-Up Telomere Repair Strategy Could Speed Identification Of Anti-Cancer Drugs
3/24/2012
Rapidly dividing cancer cells are skilled at patching up damage that would stop normal cells in their tracks, including wear and tear of telomeres, the protective caps at the end of each chromosome...
Daily Aspirin - More Benefit Than Risk?
3/24/2012
Many people take a low dose of aspirin every day to lower their risk of a further heart attack or stroke, or if they have a high risk of either. While the anticipated benefit is a lower chance of vascular disease, taking daily aspirin is not without danger: for instance it raises the risk of internal bleeding...
Photoacoustic Imaging Moves From Lab To Clinic
3/24/2012
Every new imaging technology has an aura of magic about it because it suddenly reveals what had been concealed, and makes visible what had been invisible. So, too, with photoacoustic tomography, which is allowing scientists to virtually peel away the top several inches of flesh to see what lies beneath...
Predicting Response To Platinum Chemotherapy Via Marker Of DNA Damage
3/24/2012
Scientists have uncovered a marker of DNA damage that could predict who will respond to platinum-based chemotherapy drugs like cisplatin or carboplatin. These drugs are widely used for ovarian cancer, but as with most cancer drugs, it can be difficult to predict who will respond to therapy...
Predicting Chemo Side Effects - Understanding Individual Genetic Variations
3/23/2012
Researchers have discovered a method that allows scientists to predict which patients are most likely to suffer serious side effects from chemotherapy. The finding was made in the currently largest study ever on the effects of genetic variability on the toxicity of chemotherapy in breast cancer...
Plerixafor Improves Acute Myeloid Leukemia Chemo Efficacy
3/23/2012
According to a study published in the journal Blood, researchers at Washington University School of Medicine in St. Louis have demonstrated that an investigational drug called plerixafor makes chemotherapy more effective in treating acute myeloid leukemia, a cancer of the white blood cells...
Potential Combination Therapy For Esophageal Cancer
3/23/2012
Researchers have identified a non-traditional pathway for stimulating a cancer-promoting protein into the cell nucleus that could be a potential combination therapy for esophageal cancer. The finding suggests a resistance mechanism for new drugs that attack the Hedgehog pathway...