Anti-Leukemic Effect Of Novel Compound Demonstrated In Zebrafish, Shows Promise For Human Treatment
4/11/2012
A novel anti-leukemia compound with little toxicity successfully treated zebrafish with T-cell acute lymphoblastic leukemia (T-ALL), suggesting its potential to become a new highly targeted therapy for humans - even those resistant to conventional therapies - according to results from a study published online in Blood, the Journal of the American Society of Hematology (ASH)...
Risky Treatments With Larger Rewards Preferable To 'Safe Bets' For Cancer Patients
4/11/2012
A new analysis provides a closer look at how much cancer patients value hope - with important implications for how insurers value treatment, particularly in end-of-life care...
Targeting Single-Cell Cancer With 'Nanobubbles' Plus Chemotherapy
4/11/2012
Using light-harvesting nanoparticles to convert laser energy into "plasmonic nanobubbles," researchers at Rice University, the University of Texas MD Anderson Cancer Center and Baylor College of Medicine (BCM) are developing new methods to inject drugs and genetic payloads directly into cancer cells...
New Insight Into Cell Motility
4/11/2012
Cells on the move reach forward with lamellipodia and filopodia, cytoplasmic sheets and rods supported by branched networks or tight bundles of actin filaments. Cells without functional lamellipodia are still highly motile but lose their ability to stay on track, report researchers at the Stowers Institute for Medical Research in the online issue of the Journal of Cell Biology...
Improving The Delivery Of Standard Chemotherapy Drugs By Normalizing Tumor Blood Vessels
4/11/2012
Combining two strategies designed to improve the results of cancer treatment - antiangiogenesis drugs and nanomedicines - may only be successful if the smallest nanomedicines are used...
River Blindness Causing Black Flies May Aid In Treatment Of Heart Attacks
4/11/2012
Black flies drink blood and spread disease such as river blindness - creating misery with their presence. A University of Georgia study, however, proves that the pesky insects can be useful. Don Champagne, an entomology professor with the UGA College of Agricultural and Environmental Sciences, discovered a way to use the black fly's blood-sucking tactics for medical advancement...
New Policies Aimed At Controlling Costs Should Not Follow 'One Size Fits All' Approach
4/11/2012
In the current hyper-charged United States healthcare debate, the focus on lowering cost without compromising quality of care remains a priority. But according to a new study by researchers at NYU Langone Medical Center and colleagues, one common approach may have serious unintended consequences...
Link Between 2 Genetic Deletions In Human Genome And The Development Of Aggressive Prostate Cancer
4/11/2012
An international research team led by Weill Cornell Medical College investigators have discovered two inherited-genetic deletions in the human genome linked to development of aggressive prostate cancer...
Major Source Of Cells' Defense Against Oxidative Stress Identified
4/11/2012
Both radiation and many forms of chemotherapy try to kill tumors by causing oxidative stress in cancer cells. New research from USC on a protein that protects cancer and other cells from these stresses could one day help doctors to break down cancer cells' defenses, making them more susceptible to treatment. In the Journal of Biological Chemistry, scientists led by USC Professor Kelvin J. A...
Critical Genes Mutated In Stomach Cancer Identified
4/11/2012
An international team of scientists, led by researchers from the Duke-NUS Graduate Medical School (Duke-NUS) in Singapore and National Cancer Centre of Singapore, has identified hundreds of novel genes that are mutated in stomach cancer, the second-most lethal cancer worldwide...