Spotting Breast Cancer Risk Years Before It Occurs
5/02/2012
Scientists from Imperial College London say that women with very high levels of methylation in an area of a gene, known as ATM, had double the risk of going on to develop breast cancer, compared to those without the faulty gene...
Researchers Identify Drivers Of Sarcoma Growth And Survival
5/02/2012
To better understand the signaling pathways active in sarcomas, researchers at Moffitt Cancer Center used state-of-the-art mass spectrometry-based proteomics to characterize a family of protein enzymes that act as "on" or "off" switches important in the biology of cancer. The tyrosine kinases they identified, the researchers said, could act as "drivers" for the growth and survival of sarcomas...
Gay Men And Minorities Have Poorer Quality Of Life After Prostate Cancer Treatment
5/02/2012
To improve the quality of life in gay men and minorities treated for prostate cancer, a greater awareness of ethnic and sexual preference-related factors is needed to help men choose a more-suitable treatment plan, researchers from Thomas Jefferson University Hospital conclude in a literature review published in Nature Reviews Urology...
Survival Gap Closes For Young African-American Cancer Patients With Equal Access To Care
5/02/2012
A new analysis from St. Jude Children's Research Hospital adds to evidence that equal access to comprehensive treatment and supportive care typically translates into equally good outcomes for most young African-American and white cancer patients. Researchers found no significant difference in survival rates between African-American and white children treated at St...
Disease Fighting Properties Of Lactoferrin: Heals Wounds, Boosts Immunity And Protects From Cancer
5/02/2012
Hans Vogel, a professor in the biological sciences department, is the guest editor of a special issue of the journal Biochemistry and Cell Biology that focuses on lactoferrin, an important iron-binding protein with many health benefits. "Some people describe this protein as the 'Swiss army knife' of the human host defense system," says Vogel...
Researchers Urge More Patient-Centered Care For African-American Breast Cancer Survivors
5/02/2012
African-American breast cancer survivors were satisfied with their cancer treatment, but most were never offered clinical trials opportunities or support services during or after their treatment, according to a study by a UC Davis Comprehensive Cancer Center researcher and her community partner, Rev. Tammie Dynse...
Historically, fly and human Polycomb proteins were considered textbook exemplars of transcriptional repressors, or proteins that silence the process by which DNA gives rise to new proteins. Now, work by a team of researchers at the Stowers Institute for Medical Research challenges that dogma...
Lymphoma Therapy Could Deliver A Double Punch
5/02/2012
B cell lymphomas are a group of cancers of that originate in lymphoid tissue from B cells, the specialized immune cell type that produces antibodies. The development of B cell lymphoma is associated with several known genetic changes, including increased expression of MYC, a transcription factor that promotes cell growth and division...
Research led by St. Jude Children's Research Hospital investigators suggests that safeguarding cell survival and maintaining a balanced immune system is just the start of the myeloid cell leukemia sequence 1 (MCL1) protein's work...
Gene Involved In Fanconi Anemia
5/02/2012
Scientists of KIT and the University of Birmingham have identified relevant new functions of a gene that plays a crucial role in Fanconi anemia, a life-threatening disease. The FANCM gene is known to be important for the stability of the genome. Now, the researchers found that FANCM also plays a key role in the recombination of genetic information during inheritance...