After Stem Cell Transplant For Multiple Myeloma Patients, Lenalidomide Prolongs Disease Control
5/16/2012
Multiple myeloma patients are better equipped to halt progression of this blood cancer if treated with lenalidomide, or Revlimid®, following a stem cell transplant, according to a study co-authored by a physician with the Oregon Health & Science University Knight Cancer Institute...
Apigenin Slowed Progression Of Breast Cancer Accelerated By Hormone Replacement Therapy
5/16/2012
Apigenin, a natural substance found in grocery store produce aisles, shows promise as a non-toxic treatment for an aggressive form of human breast cancer, following a new study at the University of Missouri. MU researchers found apigenin shrank a type of breast cancer tumor that is stimulated by progestin, a synthetic hormone given to women to ease symptoms related to menopause...
Marker To Identify, Attack Breast Cancer Stem Cells
5/16/2012
Breast cancer stem cells wear a cell surface protein that is part nametag and part bull's eye, identifying them as potent tumor-generating cells and flagging their vulnerability to a drug, researchers at The University of Texas MD Anderson Cancer Center report online in Journal of Clinical Investigation...
In Outcome Of Prostate Cancer Surgery, Higher Hospital Volume More Important Than Surgeon Experience
5/16/2012
Older, sicker, high-risk patients who undergo one of the most common treatments for prostate cancer get better results in larger, busier hospitals, according to new research by Henry Ford Hospital. In such cases, the same research showed the experience level of the surgeon doing the procedure mattered somewhat less than the hospital setting...
Clinical Guidance Remains Non-Specific For Drugs To Reduce Bone Cancer Damage
5/16/2012
Bone cancer-related fractures and pain can be reduced by drug treatment, but no one drug is superior, according to a review published in The Cochrane Library. Researchers undertook a systematic review of the current evidence on bisphosphonate drugs, which are used to prevent bone damage in multiple myeloma...
News From The Journal Of Clinical Investigation: May 15, 2012
5/16/2012
DEVELOPMENT Hope for new treatment options for the rare disease Beare-Stevenson syndrome Beare-Stevenson cutis gyrata syndrome is an extremely rare genetic disease that causes serious physical problems affecting the skin and skull...
Revlimid (Lenalidomide) For Myeloma - Phase III Study Findings
5/16/2012
An evaluation of lenalidomide's (Revlimid) long-term 'maintenance' efficacy for patients with multiple myeloma has demonstrated considerable improvements from the time to progression and overall survival for those suffering from this often-fatal form of hematologic cancer. The May 10 issue of the New England Journal of Medicine reports that Dr. Philip L...
Eye Cancer Tumors Likely To Spread Can Be Identified By Genetic Test
5/16/2012
Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common form of eye cancer will spread to other parts of the body, particularly the liver...
Discovery Of New Gene Mutations Leads To Breakthrough In Understanding The Cause Of Bile Duct Cancer
5/16/2012
A team of international scientists has made a significant breakthrough in understanding the cause of bile duct cancer, a deadly type of liver cancer. By identifying several new genes frequently mutated in bile duct cancers, researchers are paving the way for better understanding of how bile duct cancers develop. Their discovery is published online in Nature Genetics...
Breast Imaging And Reporting Data Systems, And MRI In Predicting Breast Cancer: Study
5/16/2012
A large, multicenter study found that the Breast Imaging and Reporting Data Systems (BI-RADS) terminology used by radiologists to classify breast imaging results is useful in predicting malignancy in breast lesions detected with MRI. Results of the study are published online in the journal Radiology...