For some patients with muscle-invasive bladder cancer, treatment may begin before they undergo cystectomy, or surgical removal of the bladder. They may be advised by oncologists to receive chemotherapy before surgery...
Glioblastoma Classification Revision Should Improve Patient Care
5/18/2012
Radiation oncology researchers have revised the system used by doctors since the 1990s to determine the prognosis of people with glioblastoma, which is the most devastating of malignant brain tumors. The outdated system was devised for glioblastoma and related brain tumors that were treated by radiation therapy only, and it relied on clinical signs and symptoms...
A study led by researchers at Fred Hutchinson Cancer Research Center has found that a next-generation, high-speed DNA-decoding technology called high-throughput sequencing can detect the earliest signs of potential relapse in nearly twice the number of leukemia patients as compared to flow cytometry, the current gold standard for detecting minimal residual disease...
The Cause Identified Of LGL Leukemia
5/18/2012
LGL leukemia is a relatively rare, malignant blood disease of the mature T-cells and, in many cases, it is related to autoimmune diseases such as rheumatoid arthritis. The pathogenetic mechanism of the disease has been unknown and it has previously been unclear if the disease is an overreaction of the normal defense system or a malignant hematological disease...
Make Or Break For Cellular Tissues
5/18/2012
Models developed to study liquids are used to investigate the mechanics of cellular tissues, which could further our understanding of embryonic development and cancer In a study about to be published in EPJ E¹, French physicists from the Curie Institute in Paris have demonstrated that the behaviour of a thin layer of cells in contact with an unfavourable substrate is akin...
Lapatinib Combined With Cetuximab Overcomes Resistance In EGFR-Driven Tumors
5/18/2012
Targeted therapies have been studied for years, but recent laboratory research is providing robust clues about drugs that might work better in combination, particularly in treating cancers that have become resistant to therapy. That kind of information is behind a novel clinical trial at Georgetown Lombardi Comprehensive Cancer Center that combines cetuximab and lapatinib...
Positive Survival Trend Seen In Phase I Study Of Temsirolimus, Capecitabine
5/18/2012
A phase I clinical trial examining the safety of combining temsirolimus and capecitabine in advanced malignancies suggests the two agents can be given safely to patients...
More Genes Discovered In The Fight Against Breast Cancer
5/18/2012
In a study published in Nature, researchers describe nine new genes that drive the development of breast cancer. This takes the tally of all genes associated with breast cancer development to 40. The team examined all the genes in the genomes of 100 cases of breast cancer...
Established Cancer Vaccine Works Better In Tandem With FDA-Approved Kidney Transplant Drug
5/18/2012
A team from the Perelman School of Medicine and the Abramson Family Cancer Research Institute at the University of Pennsylvania found that the FDA-approved drug daclizumab improved the survival of breast cancer patients taking a cancer vaccine by 30 percent, compared to those patients not taking daclizumab. This proof-of-concept study is published this week in Science Translational Medicine...
Google Algorithm Finds Cancer Biomarkers
5/17/2012
Seven proteins that can help physicians evaluate how aggressive a patient's cancer is and whether or not they should receive chemotherapy have been identified by German researchers...