Levels Of Sex Hormones Linked To Breast Cancer Risk Reduced By Moderate Weight Loss
5/23/2012

Even a moderate amount of weight loss can significantly reduce levels of circulating estrogens that are associated with an increased risk of breast cancer, according to a study by researchers at Fred Hutchinson Cancer Research Center - the first randomized, controlled clinical trial to test the effects of weight loss on sex hormones in overweight and obese postmenopausal women,...

How A Drug-Lead Compound Kills Cancer Cells By 'Starving' Them Of Energy, Preventing Tumor Formation
5/23/2012

A team of scientists from the National University of Singapore's (NUS) Department of Biological Sciences and Mechanobiology Institute have discovered how a drug-lead compound - a compound that is undergoing preclinical trials as a potential drug - can deprive cancer cells of energy and stop them from growing into a tumour. This drug-lead compound is named BPTES...

Lung Cancer CT Screening Guidelines Revised
5/22/2012

Older, current and former heavy smokers should receive annual, low-dose CT screening, according to revised guidelines published in the Journal of the American Medical Association on Sunday. The revised guidelines follow, and in the JAMA paper are accompanied by, a systematic review of evidence on the role of CT screening for individuals at higher risk of lung cancer...

PSA Screening Benefits Few, Harms Many, Says Panel
5/22/2012

A US government-sponsored panel of independent experts that reviews evidence and develops recommendations for preventive clinical services says the harms of PSA-based testing for prostate cancer outweigh the benefits. The recommendation has provoked a strong and angry response from many patient and medical groups...

Task Force Recommends Against PSA-Based Screening For Prostate Cancer: Evidence Show Harms Of PSA Testing Outweigh The Benefits
5/22/2012

Following a period for public comment, the United States Preventive Services Task Force (USPSTF) released its final recommendation for prostate cancer screening. The Task Force now recommends against PSA-based screening for all men, regardless of age...

The Risk Of Lung Cancer Mortality In The Elderly Increased By Tuberculosis
5/22/2012

Tuberculosis independently predicts death from lung cancer in the elderly, according to a new study from researchers in Hong Kong. "There is a high incidence of both tuberculosis and lung cancer among the elderly in Hong Kong," said lead author Chi Chiu Leung, MBBS, consultant chest physician in the Tuberculosis and Chest Service of the Department of Health of Hong Kong...

Sleep Apnea Has Higher Risk Of Cancer Mortality
5/22/2012

University of Wisconsin School of Medicine and Public Health released a study today showing that those suffering from sleep apnea appear to have an increased risk of cancer mortality. Previous studies have linked the sleep disordered breathing (SBD) problems to hypertension, cardiovascular disease, depression and earlier death, but this is the first to find a link to cancer...

Statins Protect From Cancer In Heart Transplant Patients
5/22/2012

Researchers presented a study at the Heart Failure Association of the European Society of Cardiology's 2012 Heart Failure Congress in Belgrade, Serbia, which revealed that statins are linked to preventing cancer and reduce all-cause mortality risk in heart transplant recipients independent of cholesterol levels. Statins are a class of immunomodulatory drugs used to lower cholesterol levels...

Predicting Response To New Treatments In Colon Cancer
5/22/2012

The Stem Cells and Cancer Research Group headed by Dr Hector G. Palmer at the Vall d'Hebron Institute of Oncology (VHIO) has identified the molecular mechanisms that determine patients' response to certain drugs used in clinical trials for colon cancer treatment...

New Target Identified In The Rheumatoid Arthritis Battle
5/22/2012

A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence that drugs under development for diseases such as cancer could potentially be used to treat RA...