Pivotal Role For Proteins - From Helping Turn Carbs Into Energy To Causing Devastating Disease
5/27/2012

Research into how carbohydrates are converted into energy has led to a surprising discovery with implications for the treatment of a perplexing and potentially fatal neuromuscular disorder and possibly even cancer and heart disease. Until this study, the cause of this neuromuscular disorder was unknown...

Key Gene Found Responsible For Chronic Inflammation, Accelerated Aging And Cancer
5/27/2012

Researchers at NYU School of Medicine have, for the first time, identified a single gene that simultaneously controls inflammation, accelerated aging and cancer. "This was certainly an unexpected finding," said principal investigator Robert J...

Orphan Sleep Drug Findings May Lead To New Cancer Therapies
5/26/2012

A new study published in the Proceedings of the National Academy of Sciences reveals that an inexpensive "orphan drug" for the treatment of sleep disorders seems to be a potent inhibitor of cancer cells...

Telomere Stability And Carcinogenesis: An Off-Again, On-Again Relationship
5/26/2012

Previous studies in mice have demonstrated antagonistic effects of telomerase loss on carcinogenesis. Telomere attrition can promote genome instability thereby stimulating initiation of early-stage cancers, but can also inhibit tumorigenesis by promoting permanent cell growth arrest or death...

Childhood Cancer Scars Survivors Later In Life
5/26/2012

Scars left behind by childhood cancer treatments are more than skin-deep...

Breast Cancer Risk Associated With Sex Hormones Reduced By Losing Weight
5/26/2012

The Journal of Clinical Oncology has published a study online which reveals that even a moderate amount of weight loss can considerably decrease levels of circulating estrogens that are linked to a higher risk of breast cancer. Anne McTiernan, M.D., Ph.D...

Combo Of Heat Shock Protein Inhibitor And Hormonal Therapy Being Tested In Breast Cancer Clinical Trial
5/26/2012

Pushed to the brink of survival, the hyper-driven cells of a cancerous tumor tap into an ancient system that has helped organisms cope with internal stresses and environmental challenges since life began...

New Drug For Destroying Human Cancer Stem Cells
5/25/2012

Conventional cancer treatments, such as chemotherapy and radiation can cause toxic side-effects. Now, researchers have discovered that a drug called thioridazine can successfully destroy cancer stem cells in humans without these effects. Mick Bhatia, lead researcher of the study and scientific director of McMaster's Stem Cell and Cancer Research Institute in the Michael G...

Chemotherapy's Effectiveness May Be Predicted By Breast MRI
5/25/2012

Magnetic resonance imaging (MRI) provides an indication of a breast tumor's response to pre-surgical chemotherapy significantly earlier than possible through clinical examination, according to a new study published online in the journal Radiology. Women with breast cancer often undergo chemotherapy prior to surgery...

Breast Cancer Patients' Survival Influenced By Their Cardio Fitness Levels
5/25/2012

Women receiving care for breast cancer have significantly impaired cardio-pulmonary function that can persist for years after they have completed treatment, according to a study led by scientists at Duke University Medical Center...