Cabazitaxel (trade name: Jevtana®) has been approved since March 2011 in men with metastatic prostate cancer who no longer respond to conventional therapy with hormone blockers and have already been pre-treated with the cytostatic drug docetaxel...
Scientists Build A Synthetic Peptide That Overcomes Cancer Cells' Survival Defenses
5/31/2012
Scientists at the Dana-Farber/Children's Hospital Cancer Center have developed an anti-cancer peptide that overcomes the stubborn resistance to chemotherapy and radiation often encountered in certain blood cancers when the disease recurs following initial treatment...
Clue To Hepatitis B Virus Genetic Code Provided By 16th-Century Korean Mummy
5/31/2012
The discovery of a mummified Korean child with relatively preserved organs enabled an Israeli-South Korean scientific team to conduct a genetic analysis on a liver biopsy which revealed a unique hepatitis B virus (HBV) genotype C2 sequence common in Southeast Asia...
Exposure To The Common Pollutant Naphthalene May Lead To Chromosomal Damage In Children
5/31/2012
According to a new study, children exposed to high levels of the common air pollutant naphthalene are at increased risk for chromosomal aberrations (CAs), which have been previously associated with cancer. These include chromosomal translocations, a potentially more harmful and long-lasting subtype of CAs...
MabThera Confirmed As Beneficial For Treating Non-Hodgkin's Lymphoma
5/30/2012
The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has concluded, after conducting a quality review of the genetically engineered monoclonal antibody MabThera, that the batches of rituximab, the active substance of MabThera, that were produced in the U.S. at the Vacaville manufacturing site do not present a risk to public health...
Anti-Psychotic Drug For Schizophrenia May Eliminate Cancer Stem Cells
5/30/2012
Scientists have discovered that an anti-psychotic drug used to treat schizophrenia seems to eliminate cancer stem cells by helping them change into less threatening cell types. The finding, published in the journal Cell Press, was made after screening hundreds of compounds in search of those that would selectively inhibit human cancer stem cells...
Huge Childhood Cancer DNA Catalogue Released
5/30/2012
By releasing a huge catalogue of complete DNA data on childhood cancers to the global scientific community, a team at St Jude Children's Research Hospital in Memphis, Tennessee, in the US, hopes to speed up progress in finding causes and new treatments for cancer and other diseases. The catalogue contains whole genome sequences, essentially complete DNA maps, from 260 child cancer patients...
Cellular Particles Fuse With Organs Establishing An Environment Ripe For The Spread Of Cancer
5/30/2012
Cancer researchers have known for well over a century that different tumor types spread only to specific, preferred organs. But no one has been able to determine the mechanisms of organ specific metastasis, the so-called "soil and seed" theory of 1889...
New Data Published From Genomics Research On Recurrent Hepatitis B Virus Integration
5/30/2012
The Asian Cancer Research Group (ACRG) - an independent, not-for-profit company established by Eli Lilly and Company, Merck (known as MSD outside the United States and Canada) and Pfizer Inc...
Why Chemotherapy Fails
5/30/2012
The fight against cancer is not won in a single battle: Long after a cancer has been beaten into remission, it can return. The reason for this is under debate, and much is unclear...