Blocking Pathway To T-Cell Acute Lymphoblastic Leukemia-Initiating Cell Regeneration
7/04/2012
Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease...
Enlarged Brain Size, Autism, Epilepsy And Cancer Linked To Newly Found Gene Mutations
7/03/2012
According to a study published online in Nature Genetics, researchers have identified three new mutations associated with megalencephaly (enlarged brain size), cancer, autism, hydrocephalus, skin growth disorders, epilepsy, and vascular anomalies...
New Treatment For Breast Cancer Patients Cuts Radiotherapy Time In Half
7/03/2012
Several breast cancer patients could be treated in half the time after research shows that accelerated whole breast irradiation after lumpectomy is an effective treatment for ductal carcinoma in situ (DCIS). The study is published in the International Journal of Radiation Oncology-Biology-Physics. DCIS is one of the most common forms of early stage and non-invasive forms of breast cancer...
Effects Of Refusing Blood Transfusions After Cardiac Surgery
7/03/2012
Although Jehovah's Witness patients do not believe in blood transfusions, their risk of surgical complications or death after heart surgery is not greater than patients who receive blood transfusions, say researchers. The study, conducted by Gregory Pattakos, M.D., M.S., of the Cleveland Clinic, Ohio, and his team, is published in Archives of Internal Medicine...
Link Between Myelodysplastic Syndromes (MDS) And Abnormal Stem Cells
7/03/2012
Researchers at Albert Einstein College of Medicine of Yeshiva University have found that abnormal bone marrow stem cells drive the development of myelodysplastic syndromes (MDS), serious blood diseases that are common among the elderly and that can progress to acute leukemia. The findings could lead to targeted therapies against MDS and prevent MDS-related cancers...
Men With Prostate Cancer Have Treatment Regret 52 Percent Higher If They Also Have Heart Disease
7/03/2012
Prostate cancer patients with cardiovascular disease were 52 per cent more likely to regret their treatment choices than men without problems with their heart or veins, according to a study published in the July issue of the urology journal BJUI International...
Gene Therapy Drugs Topically Delivered Via Commercial Moisturizers For Skin Disease Treatment
7/03/2012
"Getting under your skin" takes on a brave new meaning thanks to Northwestern University research that could transform gene regulation...
News From The Journal Of Clinical Investigation: July 2, 2012
7/03/2012
CARDIOVASCULAR DISEASE Gene variant reduces cholesterol by two mechanisms High levels of low-density lipoprotein (LDL) cholesterol increases the risk for coronary heart disease. A variant in the human gene encoding the protein sortilin is associated with reduced plasma LDL levels and a decreased risk of heart attack...
People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will return - it's a question of when. And for far too many, it happens far too soon...
Link Between Caffeinated Coffee Consumption And Reduced Risk Of Most Common Form Of Skin Cancer
7/03/2012
Increasing the number of cups of caffeinated coffee you drink could lower your risk of developing the most common form of skin cancer, basal cell carcinoma, according to a study published in Cancer Research, a journal of the American Association for Cancer Research...