Fertility Drug Usage And Cancer Risk
7/07/2012
Women using fertility drugs who did not conceive a 10-plus week pregnancy were at a statistically significant reduced risk of breast cancer compared to nonusers; however, women using the drugs who conceived a 10-plus week pregnancy had a statistically significant increased risk of breast cancer compared to unsuccessfully treated women, but a comparable risk to nonusers, accor...
Early Stage Breast Cancer Patients Benefit From Single Dose Radiation At Time Of Surgery
7/06/2012
The NewYork-Presbyterian Hospital/Weill Cornell Medical Center is the first and only hospital in New York City that offers women with early stage breast cancer innovative INTRABEAM radiotherapy, which is administered in a single dose during surgery. Women with early stage breast cancer often undergo a lumpectomy to remove a cancerous tumor...
Neighboring Non-Cancer Cells May Contribute To Drug Resistance In Skin Cancer
7/06/2012
One of cancer's most frightening characteristics is its ability to return after treatment. In the case of many forms of cancer, including the skin cancer known as melanoma, tailored drugs can eradicate cancer cells in the lab, but often produce only partial, temporary responses in patients...
Structured Training In Simulated Environment Improves Surgical Residents' Performance In OR
7/06/2012
New research has shown that surgical residents who received structured training in a simulated environment perform significantly better when they start operating on patients. The results of the study by researchers at St...
Scientists from the Florida campus of The Scripps Research Institute have identified a series of intricate biochemical steps that lead to the successful production of proteins, the basic working units of any cell. The study, which appears in the journal Cell, sheds light on the assembly of a structure called the ribosome, a large and complex protein-producing machine inside all living cells...
Discovery Of Mechanism That Controls Obesity, Atherosclerosis And Potentially Cancer
7/06/2012
A*STAR scientists from the Institute of Molecular and Cell Biology (IMCB) and the Singapore Bioimaging Consortium (SBIC) have discovered a new signalling pathway that controls both obesity and atherosclerosis...
Spontaneous Pregnancy Achieved Following Cryopreservation And Transplant Of Ovarian Tissue
7/06/2012
Although the first successful preservation of fertility from the freezing, thawing and grafting of ovarian tissue was reported eight years ago,(1) the technique has remained experimental and confined to a few specialist centres...
Halting The Spread Of Cancer By Following The Genomic Pathways
7/06/2012
As the Genetics Society of America's Model Organism to Human Biology (MOHB): Cancer Genetics Meeting in Washington, D.C. drew to a close, it was clear that the mantra for drug discovery to treat cancers in the post-genomic era is pathways. Pathways are ordered series of actions that occur as cells move from one state, through a series of intermediate states, to a final action...
Unresponsive Aplastic Anemia Patients May Benefit From Eltrombopag
7/06/2012
Eltrombopag, a drug that was designed to stimulate production of platelets from the bone marrow and thereby improve blood clotting, can raise blood cell levels in some people with severe aplastic anemia who have failed all standard therapies. About one-third of aplastic anemia cases do not respond to standard therapy, a combination of immune-suppressing drugs...
'Oncometabolite' Linked To Onset Of Acute Myeloid Leukemia
7/06/2012
A team of international scientists led by principal investigator Dr. Tak Mak at the Princess Margaret Cancer Centre, University Health Network, has identified a causative link between the product of a mutated metabolic enzyme and the onset of acute myeloid leukemia (AML), one of the most common types of leukemia in adults...