Immune Cell DNA Utilized For Diagnostic Technique
7/11/2012
When a person is sick, there is a tell-tale sign in their blood: a different mix of the various types of immune cells called leukocytes...
Skin squamous cell carcinoma (SCC) is a subtype of very aggressive skin cancers that usually develops in sunexposed body regions, but can also affect a large number of organs such as the bladder, esophagus, lungs etc...
New Target Found Deep Within Cancer Cells
7/11/2012
Investigators reporting in the July issue of the Cell Press journal Cancer Cell have found that blocking a fundamental process deep within cancer cells can selectively kill them and spare normal cells. For more than a century, clinicians have known that abnormalities of the nucleolus - a small, rounded mass within the cell nucleus - can be diagnostic for cancer...
New Molecular Insights Lead To Improved Treatment For Brain Cancer
7/11/2012
Nearly a third of adults with the most common type of brain cancer develop recurrent, invasive tumors after being treated with a drug called bevacizumab. The molecular underpinnings behind these detrimental effects have now been published by Cell Press in the July issue of Cancer Cell...
Protein interactions outside breast cancer cells can send signals to the cancer cells to permanently stop proliferating, a new study showed in the School of Medicine at The University of Texas Health Science Center San Antonio. "Because this protein cascade is outside the cells, it is likely amenable to therapeutic manipulation," said lead author Yuzuru Shiio, M.D., Ph.D...
New MRI Technique To Help Heart Disease Patients
7/10/2012
Researchers at Edinburgh University, a British Heart Foundation (BHF) Centre of Research Excellence, have developed a new technique that is able to track cells in the bloodstream, according to a study published in the journal Circulation. The technique could be used in the future to measure the effectiveness of stem cell treatments to repair damaged heart tissue, say the researchers...
Colon Cancer Cells Use "Let Me Pass" Signals
7/10/2012
In what reads like a chilling tale of skulduggery and subterfuge, researchers writing online in the journal Cancer Cell this week, describe how colon cancer tumor cells send "let me pass" signals to make blood vessel walls permeable, thus allowing them to travel through and establish themselves in neighbouring tissue (extravasation)...
Better End Of Life Quality Of Life For Cancer Patients
7/10/2012
In many cases, when cancer patients are left with no further options to treat their disease, the focus shifts from prolonging life to promoting the quality of life (QOL) at the end of life (EOL). Now, researchers have identified factors that influence better QOL at EOL...
Brain Tumors Traced To Stem Cells In Developing Brain
7/10/2012
Stem cells that come from a specific part of the developing brain help fuel the growth of brain tumors caused by an inherited condition, researchers at Washington University School of Medicine in St. Louis report...
News From The Journal Of Clinical Investigation: July 9, 2012
7/10/2012
Breathing easy: keeping airways open Asthma is an increasingly common chronic disorder characterized by wheezing and shortness of breath. Symptoms are caused by excessive airway smooth muscle contraction; however mechanisms serving to keep airways open are not fully understood...