Lower Dose Of Cancer Drug Needed When Grapefruit Juice Prescribed
8/09/2012
A glass a day of grapefruit juice lets patients derive the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself, according to a new clinical trial. The combination could help patients avoid side effects associated with high doses of the drug and reduce the cost of the medication...
In Animal Models, TRPM7 Protein Found To Be Key To Breast Cancer Metastasis
8/09/2012
The protein transient receptor potential melastatin-like 7 (TRPM7) is a critical determinant of breast cancer cell metastasis, according to study results published in /iCancer Research, a journal of the American Association for Cancer Research...
"Pancreas In A Dish" Will Show How Pancreatic Cancer Forms
8/08/2012
A tiny, living 3-D organ model of pancreatic ducts has been created by researchers in Toronto to help them understand pancreatic cancer, which is one of the deadliest yet least understood of all cancers. This new model could lead to the discovery of new ways to detect and treat pancreatic cancer...
Grapefruit Juice Helps Anti-Cancer Drug Work Better
8/08/2012
A new clinical trial published in the August edition of Clinical Cancer Research has revealed that cancer patients who drink one glass of grapefruit juice per day achieve the same benefits from an anti-cancer drug as they would get from more than three times as much of the drug by itself...
Proteins May Point Way To New Prostate Cancer Drug Targets
8/08/2012
Two proteins that act in opposing directions - one that promotes cancer and one that suppresses cancer - regulate the same set of genes in prostate cancer, Vanderbilt-Ingram Cancer Center researchers have found. The findings, reported recently in the Journal of Clinical Investigation, point toward potential drug targets and prognostic markers for prostate cancer...
Photosensitizing Antihypertensive Drugs May Increase Risk Of Lip Cancer
8/08/2012
Long-term use of commonly used blood pressure medications that increase sensitivity to sunlight is associated with an increased risk of lip cancer in non-Hispanic whites, according to a Kaiser Permanente study that appears in the current online issue of Archives of Internal Medicine...
Diesel Soot Re-Classified As Carcinogenic, Causing Lung Cancer
8/08/2012
Since June 2012, it is official: The World Health Organisation (WHO) has classified diesel soot as a lung carcinogen. Artur Braun, a physicist at Empa and an X-ray spectroscopy expert, has made crucial contributions to analyzing the structure and composition of soot particles. Soot particles are dangerous - there is nothing new in this knowledge...
Testing Of New Drug For Patients With Neuroendocrine Tumors
8/08/2012
A researcher at Moffitt Cancer Center and his international team of colleagues have reported study results on a novel multireceptor-targeted somatostatin analogue called pasireotide (SOM230) manufactured by Novartis Pharma AG...
Greater Incidence Of Babies With Retinoblastoma In US-Born Latinas
8/08/2012
In a large epidemiologic study, researchers at UCLA's Jonsson Cancer Center found that the children of U.S.-born Latina women are at higher risk of having retinoblastoma, a malignant tumor of the retina which typically occurs in children under six...
Interactions Between Gene Mutations And The Development Of Cancer
8/08/2012
Despite a huge amount of research effort, the molecular mechanisms that underlie the transition from a "normal" cell to a cancerous cell are only poorly understood. After the discovery of the first cancer-causing genes or oncogenes and the finding that they are mutated forms of normal cellular genes, it was widely believed that a single mutation was enough to cause cancer...