Nanoparticles Shrink Ovarian Cancer Tumors In Mice
8/17/2012
By sequencing cancer-cell genomes, researchers have found a substantial amount of genes that happen to be mutated, deleted or duplicated within cancerous cells. This treasure chest is a great asset for scientists searching for innovative drug targets, however, it's extremely difficult to examine all of them promptly...
Chemotherapy During Pregnancy Does Not Affect Birth Outcomes
8/17/2012
According to a study published Online First in The Lancet Oncology, babies born to women with breast cancer who received chemotherapy while pregnant do not seem to be at greater risk of complications. The researchers analyzed over 400 women from across Europe who had been identified as having early-stage breast cancer during pregnancy...
What Is A Tumor?
8/17/2012
A tumor, also known as a neoplasm, is an abnormal mass of tissue which may be solid or fluid-filled. A tumor does not mean cancer - tumors can be benign (not cancerous), pre-malignant (pre-cancerous), or malignant (cancerous). There are many different types of tumors and a variety of names for them - their names usually reflect their shape and the kind of tissue they appear in...
By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly impossible to test them all in a timely fashion...
By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly impossible to test them all in a timely fashion...
Skin Cancer: Potential New Treatment Target Identified For Melanoma
8/17/2012
New research from Western University, Canada, has identified a potential new target for the treatment of melanoma, the deadliest of all skin cancers. Silvia Penuela and Dale Laird discovered a new channel-forming protein called Pannexin (Panx1) that is expressed in normal levels on the surface of healthy skin cells. But they found, in melanoma, Panx1 is over-produced to a pathological level...
By Studying Animal Health, Researchers Find Improved Ways For Developing, Testing Cancer Therapies
8/17/2012
A group of Kansas State University researchers has made valuable findings in the search for cancer's cure. While researching ways to improve animal health, the scientists -- Raymond "Bob" Rowland, a virologist and professor of diagnostic medicine and pathobiology, and Deryl Troyer, professor of anatomy and physiology -- have made two important discoveries that can also improve human health...
Two Approaches To Understanding The Basic Mechanics Of Cancer
8/17/2012
The genomic tumult within tumor cells has provided scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard with clues to an entirely new class of genes that may serve as an Achilles' heel for many forms of cancer. As reported in the Aug...
Simulated Blood Flow Device Provides Evidence Of How Bloodstream Infections Begin
8/17/2012
New research may help explain why hundreds of thousands of Americans a year get sick - and tens of thousands die - after bacteria get into their blood. It also suggests why some of those bloodstream infections resist treatment with even the most powerful antibiotics...
Combining BRAF Inhibitor And Immunotherapy Increases Antitumor Activity In Metastatic Melanoma
8/17/2012
BRAF Inhibitor Zelboraf Boosts Effectiveness of Immunotherapy in Mouse ModelCombining the recently approved BRAF inhibitor, Zelboraf with an engineered T cell immunotherapy to treat metastatic melanoma significantly increased tumor responses and survival in an animal model, researchers at UCLA's Jonsson Comprehensive Cancer Center have shown...