Experimental Vaccine Therapies Complicated By Cancer 'Turning Off' Important Immune Cells
9/03/2012
A research report published in the September 2012 issue of the Journal of Leukocyte Biology offers a possible explanation of why some cancer vaccines are not as effective as hoped, while at the same time identifies a new therapeutic strategy for treating autoimmune problems...
A Possible Therapy For Tamoxifen-Resistant Breast Cancer Identified
9/03/2012
A study by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) has discovered how tamoxifen-resistant breast-cancer cells grow and proliferate. It also suggests that an experimental agent might offer a novel targeted therapy for tamoxifen-resistant breast cancer...
Diverse Metabolic Roles Revealed For PML Tumor Suppressor Gene
9/03/2012
Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer treatment...
Microcirculation Of Malaria-Infected Red Blood Cells Impeded By Protein
9/03/2012
When the parasite responsible for malaria infects human red blood cells, it launches a 48-hour remodeling of the host cells. During the first 24 hours of this cycle, a protein called RESA undertakes the first step of renovation: enhancing the stiffness of the cell membranes...
May enhance evaluation of cancer risk in the up to 1...
Mechanism Discovered That Leads From Trichomoniasis To Prostate Cancer
9/01/2012
Researchers have identified a way in which men can develop prostate cancer after contracting trichomoniasis, a curable but often overlooked sexually transmitted disease. Previous studies have teased out a casual, epidemiological correlation between the two diseases, but this latest study suggests a more tangible biological mechanism...
May enhance evaluation of cancer risk in the up to 1...
Cancer Gene Family Member Functions Key To Cell Adhesion And Migration
9/01/2012
The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C...
2 Chemo Drugs For Breast Cancer May Cause Heart Problems
9/01/2012
Women who have breast cancer and are treated with two chemotherapy drugs may experience more cardiac problems like heart failure than shown in previous studies, according to a new Cancer Research Network study by Group Health researchers and others in the Journal of the National Cancer Institute...
Johns Hopkins researchers have created a synthetic protein that, when activated by ultraviolet light, can guide doctors to places within the body where cancer, arthritis and other serious medical disorders can be detected...