Researchers Find Cause Of Chemotherapy Resistance In Melanoma
9/19/2012
Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy. UCI dermatologist Dr. Anand Ganesan and colleagues found a genetic pathway in melanoma cells that inhibits the cellular mechanism for detecting DNA damage wrought by chemotherapy, thereby building up tolerance to cancer-killing drugs...
In HER2-Positive Breast Cancers, PARP Inhibitors May Have Clinical Utility
9/19/2012
Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive breast cancers, according to the results of a study published in Cancer Research, a journal of the American Association for Cancer Research...
The power of taxane-based chemotherapy drugs are misunderstood and potentially underestimated, according to researchers at Weill Cornell Medical College in the journal Cancer Research...
Children And Their Families Coping With Life-Threatening Illnesses Rewarded With Legacy Beads
9/19/2012
When Kayla Dehnert tells friends and family in Northern California about life as a St. Jude Children's Research Hospital patient, she pulls out a string of beads taller than she is. "This is a learning-to-take medicine bead," Kayla explains, fingering the bumps of a bluish-lavender bead and working her way down the long strand...
Vitamin E May Decrease Cancer Risk In Cowden Syndrome Patients
9/19/2012
Cleveland Clinic researchers have discovered that vitamin E may prevent cancer in patients with an under-recognized genetic disorder. Several genetic mutations are known to be present in Cowden Syndrome (CS) - a disease that predisposes individuals to several types of cancers, including breast and thyroid cancers...
A new study published online in Nature Medicine, led by scientists at The University of Texas MD Anderson Cancer Center, describes the discovery of a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options. Melanoma patients have different responses to therapy, depending on what genes are mutated in their tumors...
No Evidence Of Health Risk Found For Proximity To Mobile Phones And Wireless Networks
9/19/2012
There is no scientific evidence that low-level electromagnetic field exposure from mobile phones and other transmitting devices causes adverse health effects, according to a report presented by a Norwegian Expert Committee. In addition, the Committee provides advice to authorities about risk management and regulatory practice...
Shingles And Cancer Risk
9/19/2012
Herpes zoster, or shingles, does not increase the risk of cancer in the general population, according to a study in CMAJ (Canadian Medical Association Journal). Although herpes zoster is more common in patients with cancer than in those without, it is unknown whether the risk of cancer is increased for people with herpes zoster...
In HER2-Positive Breast Cancers, PARP Inhibitors May Have Clinical Utility
9/19/2012
Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive breast cancers, according to the results of a study published in Cancer Research, a journal of the American Association for Cancer Research...
Breast Cancer Risk Linked To Early-Life Diet, Metabolic Syndrome
9/19/2012
Striking new evidence suggesting that diet and related factors early in life can boost the risk for breast cancer - totally independent of the body's production of the hormone estrogen - has been uncovered by a team of researchers at the University of California, Davis...