Researcher Discovers Homing Device That Attracts Melanoma To The Brain
9/21/2012

The process of metastasis, by which cancer cells travel from a tumor site and proliferate at other sites in the body, is a serious threat to cancer patients. According to the National Cancer Institute, most recurrences of cancer are metastases rather than "new" cancers. Virtually all types of cancer can spread to other parts of the body, including the brain...

A Few 'Hotspots' On The Human Genome Revealed By Diseases Of Aging Map
9/21/2012

Researchers have long known that individual diseases are associated with genes in specific locations of the genome. Genetics researchers at the University of North Carolina School of Medicine now have shown definitively that a small number of places in the human genome are associated with a large number and variety of diseases...

Pharmacodynamic Response Predicted By Genetically-Engineered Preclinical Models, Essential For Cancer Drug Development
9/21/2012

New cancer drugs must be thoroughly tested in preclinical models, often in mice, before they can be offered to cancer patients for the first time in phase I clinical trials. Key components of this process include pharmacokinetic and pharmacodynamic studies, which evaluate how the drug acts on a living organism...

How Cancer Is Portrayed In The Movies Needs To Change - It Isn't Always A Death Sentence
9/21/2012

Films that feature characters with cancer have become a familiar sight for movie-goers in recent years, but they rarely portray the patient's chances of survival accurately, Italian reserachers will report at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna, Austria...

An International 'Dream Team' Against Breast Cancer
9/21/2012

The Vall d'Hebron Breast Cancer Unit, the Vall d'Hebron Institute of Oncology (VHIO) and SOLTI, an academic breast cancer research group , are heading up a multi-centre international study involving four Spanish and three North American research centres*...

Decorin, A Well-Studied Protein, Induces Tumor Suppressor Genes In Microenvironment To Stop Metastasis In Triple Negative Breast Cancer
9/21/2012

A natural substance found in the surrounding tissue of a tumor may be a promising weapon to stop triple negative breast cancer from metastasizing...

Researchers Clarify Catalysis Mechanism Of Cell Growth Protein Ras
9/20/2012

PNAS: Proteins bring tension to the phosphate chain Proteins accelerate certain chemical reactions in cells by several orders of magnitude. The molecular mechanism by which the Ras protein accelerates the cleavage of the molecule GTP and thus slows cell growth is described by biophysicists at the Ruhr-Universität Bochum led by Prof. Dr...

Assessment Of HPV DNA Alone Insufficient To Identify HPV-Driven Head And Neck Cancers
9/20/2012

Human papillomavirus (HPV) DNA positivity alone, particularly when assessed using polymerase chain reaction methods, is a poor biomarker for HPV-driven head and neck cancers, according to two studies published in Cancer Research, a journal of the American Association for Cancer Research...

Snake Venom Could Unlock Drug Discoveries For Cancer, Diabetes
9/20/2012

A new revelation has been discovered, claiming that toxins in snake venom could potentially open doors to cutting-edge drugs being able to treat severe medical conditions, such as diabetes, high blood pressure, and cancer...

Contamination Led To Erroneous Link Between XMRV And Prostate Cancer
9/20/2012

A once-promising discovery linking prostate cancer to an obscure retrovirus derived from mice was the result of an inadvertent laboratory contamination, a forensic analysis of tissue samples and lab experiments - some dating back nearly a decade - has confirmed...