In Atrial Fibrillation, Undertreatment Persists Despite Rapid Adoption Of Novel Therapies
9/25/2012
A novel blood thinner recently approved by the FDA, dabigatran (Pradaxa), has been rapidly adopted into clinical practice, yet thus far has had little impact on improving treatment rates for atrial fibrillation. This is according to a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health that examined national trends in oral anticoagulant use...
It's a high-pressure environment within solid tumors. Abnormal blood and lymphatic vessels cause fluids to accumulate, and the uncontrolled proliferation of cancer cells within limited space leads to the buildup of what is called solid stress...
MDC Researchers Solve Puzzle Of B-Cell Lymphoma Development
9/24/2012
The Myc gene is a key regulator of cellular proliferation and is frequently involved in chromosomal translocations in human lymphomas derived from B cells at the germinal center reaction...
Unexpected New Way To Produce Nylon Discovered During Cancer Research
9/24/2012
In their quest for a cancer cure, researchers at the Duke Cancer Institute made a serendipitous discovery -- a molecule necessary for cheaper and greener ways to produce nylon. The finding, described in the journal Nature Chemical Biology, arose from an intriguing notion that some of the genetic and chemical changes in cancer tumors might be harnessed for beneficial uses...
Camptothecin Analog FL118 Shown To Inhibit Production Of Key Cancer Survival Genes
9/24/2012
Some 500,000 people die of cancer in the United States each year, often because their cancers have become resistant to approved therapies...
Young Cancer Survivors Often Forgo Medical Care Due To Costs
9/24/2012
Many survivors of adolescent and young adult cancers avoid routine medical care because it's too expensive, despite the fact that most have health insurance. That is the conclusion of a new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society...
It's a high-pressure environment within solid tumors. Abnormal blood and lymphatic vessels cause fluids to accumulate, and the uncontrolled proliferation of cancer cells within limited space leads to the buildup of what is called solid stress...
Leukemia With Poor Prognoses: New Therapeutic Strategy Leads To Clinical Trial, Drug Development
9/24/2012
Investigators at Northwestern University Feinberg School of Medicine have identified two promising therapies to treat patients with acute megakaryocytic leukemia (AMKL), a rare form of leukemia where the number of cases is expected to increase with the aging population...
Biologists Gain New Insight Into Migrating Cells
9/24/2012
At any given moment, millions of cells are on the move in the human body, typically on their way to aid in immune response, make repairs, or provide some other benefit to the structures around them. When the migration process goes wrong, however, the results can include tumor formation and metastatic cancer...
Obese People Can Be Metabolically Healthy And In Good Shape
9/24/2012
A person can be obese and metabolically healthy at the same time, which means that this person will have the same mortality risk for heart disease or cancer as people of normal weight. This is the conclusion of a study published in the prestigious journal European Heart Journal [1]. "Obesity is associated with a large number of chronic diseases as heart diseases or cancer...