Across A Range Of Patient Risk Scores, Apixaban Found To Be Superior To Warfarin
10/03/2012

A new anticoagulant called apixaban is superior to warfarin in preventing stroke with consistent effects across a wide range of stroke and bleeding risk in patients with atrial fibrillation, according to Duke University Medical Center researchers...

Drug Trials Seek Combinations Effective For Melanoma
10/02/2012

Promising new data from trials aimed at delaying resistance to BRAF inhibitors Promising new data on drug combinations to treat metastatic melanoma were presented at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna...

Subcutaneous VELCADE® Approved In The EU For The Treatment Of Multiple Myeloma
10/02/2012

Janssen-Cilag International NV (Janssen) has announced that the European Commission has granted marketing authorisation for the subcutaneous (under the skin) administration of VELCADE® (bortezomib) in the European Union. Bortezomib is indicated for the treatment of multiple myeloma, a type of blood cancer...

In MISSION Trial Sorafenib Not Found To Extend Overall Survival As Third Or Fourth Line Therapy In Lung Cancer
10/02/2012

Phase III MISSION trial - EGFR status may help select patients who will benefit most Treatment with the drug sorafenib as a third or fourth line therapy does not result in improved overall survival among patients with advanced non-small cell lung cancer (NSCLC), according to findings released at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna...

Use Of Interstitial Fluid Pressure Via Noninvasive Measurement, A Potential Biomarker For Tumor Aggressiveness
10/02/2012

Researchers validated a method of noninvasive imaging that provides valuable information about interstitial fluid pressure of solid tumors and may aid in the identification of aggressive tumors, according to the results of a study published in Cancer Research, a journal of the American Association for Cancer Research...

Oral Palonosetron Shows Safe And Effective Control Of Nausea And Vomiting Induced By Multiple Cycles Of Chemotherapy
10/02/2012

New data presented at the 2012 meeting of the European Society of Medical Oncology (ESMO) in Vienna show antiemetic efficacy maintained across the chemotherapy cycles and a positive safety profile The oral formulation of palonosetron, the second generation 5-HT3 receptor antagonist (5-HT3 RA), is effective and safe in preventing chemotherapy-induced nausea and vomiting (...

Northwest Bio Proceeding With A Phase I/Ii Clinical Trial Of Dcvax®-Direct For All Solid Tumor Cancers
10/02/2012

Northwest Biotherapeutics (OTC.BB: NWBO) (NW Bio), a biotechnology company developing DCVax® personalized immune therapies for cancer, announced today that it is in late stage discussions with medical centers in the U.S. and Europe to proceed with a Phase I/II clinical trial with the Company's third major product line, DCVax®-Direct, for all types of solid tumor cancers (i.e...

Merck Serono: Detailed Results Presented From Study Of Erbitux In Advanced Gastric Cancer (EXPAND)
10/02/2012

Merck Serono, a division of Merck, Darmstadt, Germany, presented detailed results from the Phase III EXPAND* trial, at the ESMO 2012 Congress (European Society for Medical Oncology) in Vienna, Austria, September 28 - October 2, 2012. First results of this study were already announced in July 2012...

Most Cancer Patients Prepared To Delay Treatment To Benefit From Personalized Care
10/02/2012

Merck Serono, a division of Merck, Darmstadt, Germany, have announced findings from a new multinational survey of patient awareness and understanding of biomarker-led personalized cancer care presented at the ESMO 2012 Congress (European Society for Medical Oncology)...

ImmunoGen, Inc. Announces Overall Survival Data Reported For Trastuzumab Emtansine (T-DM1) Phase III EMILIA Trial
10/02/2012

ImmunoGen, Inc. (Nasdaq: IMGN), a biopharmaceutical company that develops anticancer products using its Targeted Antibody Payload (TAP) technology and antibody expertise, have announced the presentation of overall survival (OS) data from the trastuzumab emtansine Phase III trial, EMILIA...