Two-Drug Synergy Investigated For Treatment Of Drug-Resistant Chronic Myeloid Leukemia
10/26/2012
An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together to overcome resistance in the BCR-ABL gatekeeper mutation-specific disease...
Study Finds Advanced Cancer Patients Overoptimistic About Chemotherapy's Ability To Cure
10/26/2012
Findings from a nationwide study led by researchers at Dana-Farber Cancer Institute suggest that patients with advanced lung or colorectal cancer are frequently mistaken in their beliefs that chemotherapy can cure their disease...
Colorectal Cancer Patients With Gene Mutation Live Longer With Aspirin Therapy
10/26/2012
Aspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but has no effect on patients who lack the mutation, Dana-Farber Cancer Institute scientists report in the New England Journal of Medicine...
Discovery Of Potential Tumor And Metastasis Suppressor In Breast Cancer
10/26/2012
A protein that is necessary for lactation in mammals inhibits the critical cellular transition that is an early indicator of breast cancer and metastasis, according to research conducted at the University at Buffalo and Princeton University and highlighted as the cover paper in November issue of Nature Cell Biology...
Prasugrel May Benefit Patients Triaged To Medical Therapy Following Angiography
10/26/2012
Prasugrel, a novel anti-platelet therapy, is used to prevent recurrent cardiovascular events in patients who have had a prior heart attack, suffer severe chest pain and have been treated with coronary artery procedures (revascularization)...
Advanced Melanoma Tumors Eradicated In Mouse Model
10/26/2012
Cancers arise in the body all the time. Most are nipped in the bud by the immune response, not least by its T cells, which detect telltale molecular markers - or antigens - on cancer cells and destroy them before they grow into tumors. Cancer cells, for their part, evolve constantly to evade such assassination. Those that succeed become full-blown malignancies...
Two-Drug Synergy Investigated For Treatment Of Drug-Resistant Chronic Myeloid Leukemia
10/26/2012
An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together to overcome resistance in the BCR-ABL gatekeeper mutation-specific disease...
Half A Billion People Exposed To Direct Carcinogens By Chewing Betel Quid
10/26/2012
Chewing betel quid - the fourth most popular psychoactive substance in the world after tobacco, alcohol and caffeine - exposes its 600 million users to substances that act as direct carcinogens in the mouth, scientists are reporting in a new study. It appears in ACS' journal Chemical Research in Toxicology...
Study Finds Advanced Cancer Patients Overoptimistic About Chemotherapy's Ability To Cure
10/26/2012
Findings from a nationwide study led by researchers at Dana-Farber Cancer Institute suggest that patients with advanced lung or colorectal cancer are frequently mistaken in their beliefs that chemotherapy can cure their disease...
Colorectal Cancer Patients With Gene Mutation Live Longer With Aspirin Therapy
10/26/2012
Aspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but has no effect on patients who lack the mutation, Dana-Farber Cancer Institute scientists report in the New England Journal of Medicine...