Prostate Cancer Recurrence More Likely When Testosterone Drops After Radiation
10/29/2012

Men whose testosterone drops following radiation therapy for prostate cancer are more likely to experience a change in PSA levels that signals their cancer has returned, according to new research from Fox Chase Cancer Center. The findings will be presented on October 29 at the American Society for Radiation Oncology's 54th Annual Meeting...

Genetic Mutations Tested In Zebrafish
10/29/2012

The zebrafish is a potential tool for testing one class of unique individual genetic differences found in humans, and may yield information helpful for the emerging field of personalized medicine, according to a team led by Penn State College of Medicine scientists...

Spread Of Rectal Cancer To Lymph Nodes More Likely At Younger Age
10/29/2012

Rectal cancer is more likely to spread to the lymph nodes in younger patients, according to new findings that Fox Chase Cancer Center researchers will be presenting on October 29 at the American Society for Radiation Oncology's 54th Annual Meeting. The results - which are the first of their kind - suggest that doctors should search for spreading more aggressively in these patients...

New Options For Ease And Accuracy In Extraction Of Rare Cells Or Separating Blood Offered By Microfluidic Breakthroughs
10/29/2012

At the Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS) held Oct. 28-Nov. 1, in Okinawa, Japan, University of Cincinnati researchers present four papers, including one detailing improvements in rare cell isolation and one detailing improvements, in terms of cost and time, of common blood tests...

Multifocal/Multicentric Breast Cancer Connected To A Patient's Risk Of Local Recurrence
10/29/2012

Not all women diagnosed with operable breast cancer present with a single tumor; some have multifocal disease appear in the breast, which means multiple tumors found in the same breast quadrant, while others have multicentric disease, where multiple tumors are found in separate breast quadrants. Multifocal or multicentric disease is not a standard indication to receive radiation after mastectomy...

Intracoronary And Intravenous Use Of Abciximab During Angioplasty Yield Similar Results
10/29/2012

Results of the AIDA STEMI MRI sub-study presented at TCT 2012 A study confirmed no differences in various measures of heart damage, according to cardiac magnetic resonance (MRI) imaging, in patients receiving the anti-clotting medication abxicimab directly into the heart (intracoronary) compared to those receiving it intravenously (IV)...

Key Regulatory Pathways Of Myeloid Differentiation Identified
10/29/2012

Associate Professor of Cell and Developmental Biology Fei Wang and colleagues have created a new technique to study how myeloids, a type of blood stem cell, become the white blood cells important for immune system defense against infections and tissue damage...

New Anti-Tumor Cell Therapy Strategies Are More Effective
10/29/2012

Targeted T-cells can seek out and destroy tumor cells that carry specific antigen markers. Two novel anti-tumor therapies that take advantage of this T-cell response are described in articles published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The articles are available free on the Human Gene Therapy website...

Major Flaw Identified In Standard Approach To Global Gene Expression Analysis
10/29/2012

Whitehead Institute researchers report that common assumptions employed in the generation and interpretation of data from global gene expression analyses can lead to seriously flawed conclusions about gene activity and cell behavior in a wide range of current biological research...

New Nano Drug Delivery System Developed For Bladder Cancer
10/29/2012

A team of UC Davis scientists has shown in experimental mouse models that a new drug delivery system allows for administration of three times the maximum tolerated dose of a standard drug therapy for advanced bladder cancer, leading to more effective cancer control without increasing toxicity...