Predicting Tamoxifen Resistance In Breast Cancer Treatment
11/02/2012
Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen. Tamoxifen - used alongside traditional chemotherapy and radiotherapy - blocks the female hormone oestrogen that, in certain breast cancers, is required by the tumour to grow; it has been shown to improve cancer survival rates by up to one third...
For Best Outcomes In Stroke, Near-Complete Blood Flow Restoration Critical
11/02/2012
Two Rhode Island Hospital researchers recently found that restoring near-complete blood flow to the brain is necessary to restore or preserve neurological function following stroke. Seems like a no-brainer, right? Yet until their research was complete, many physicians and researchers believed that partial blood-flow restoration was good enough. Not anymore. The study by Mahesh Jayaraman, M...
Total Number Of Lymphocytes Tied To Outcome In Merkel Cell Carcinoma
11/02/2012
A routine blood test may help predict survival in patients with an aggressive form of skin cancer known as Merkel cell carcinoma, according to new findings by Fox Chase Cancer Center researchers. The results were presented at the American Society for Radiation Oncology's 54th Annual Meeting...
In Red-Haired, Fair-Skinned Individuals, An Unexpected Factor Contributes To Melanoma Risk
11/02/2012
The well-established elevated risk of melanoma among people with red hair and fair skin may be caused by more than just a lack of natural protection against ultraviolet (UV) radiation...
Effective Healthcare Can Reduce Toll From Major Diseases Like Stroke, Heart Disease And Cancer
11/02/2012
Research led by University of Leicester discovers how effective healthcare can reduce toll from major diseases like stroke, heart disease and cancer Wide differences in death rates from disease still persist throughout England - but effective healthcare can help to reduce these inequalities, a new study has discovered...
Unlocking The Secrets Of DNA Repair
11/02/2012
Scientists from the University of Sheffield have unlocked one of the secrets to DNA repair - helping doctors identify DNA base damage and a patient's susceptibility to certain types of cancer...
Non-Invasive Stereotactic Radiosurgery Shows Promise For Kidney Cancer
11/02/2012
A first-of-its-kind clinical trial conducted at University Hospitals (UH) Case Medical Center Seidman Cancer Center has shown encouraging results for the use of stereotactic radiosurgery to treat kidney cancer. This non-invasive treatment technique may represent a potential new non-surgical option for patients with this deadly disease who have limited treatment options...
Antisense Technology That Exploits Gene Splicing Mechanism Used To Kill Cancer Cells
11/02/2012
Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. To do this they need to speed up their metabolism...
Gastrointestinal Cancers Likely Reduced By Consumption Of Green Tea
11/02/2012
Women who drink green tea may lower their risk of developing some digestive system cancers, especially cancers of the stomach/esophagus and colorectum, according to a study led by researchers from Vanderbilt-Ingram Cancer Center. The study by lead author Sarah Nechuta, Ph.D., MPH, assistant professor of Medicine, was published online in advance of the Nov...
Predicting Tamoxifen Resistance In Breast Cancer Treatment
11/02/2012
Scientists have identified a molecular 'flag' in women with breast cancer who do not respond or have become resistant to the hormone drug tamoxifen. Tamoxifen - used alongside traditional chemotherapy and radiotherapy - blocks the female hormone oestrogen that, in certain breast cancers, is required by the tumour to grow; it has been shown to improve cancer survival rates by up to one third...