Promising Results In Cell, Animal Model In Targeting Downstream Proteins In Cancer-Causing Pathway
11/16/2012
The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell's powerhouse, making it dependent on the amino acid glutamine for survival. In fact, 40 percent of all "hard-to-treat" cancers have a mutation in the Myc gene. Accordingly, depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc...
Discovery Of How Stomach Cancer Spreads
11/16/2012
Scientists at the University of Liverpool have found that the production of a protein that prevents the growth and spread of cancerous cells is impaired in patients with gastric cancer. Cancer of the stomach is the second most common cause of death due to malignant disease worldwide...
Ingredients For A Successful Cell Death: A Sip Of Resveratrol And A Full P53
11/16/2012
Resveratrol is a naturally occurring dietary compound found in grapes, berries, and peanuts. This polyphenol protects plants against pathogens such as bacteria and fungi by inducing cell death in invading organisms. The compound was discovered in red wine in 1939 but by large did not attract the attention of the scientific community...
Cancer Symptoms May Be Eased By Ancient Foot Massage Technique
11/16/2012
A study led by a Michigan State University researcher offers the strongest evidence yet that reflexology - a type of specialized foot massage practiced since the age of pharaohs - can help cancer patients manage their symptoms and perform daily tasks...
Certain Subgroups Of Black Women Have Lower Uptake Of HPV Vaccination
11/16/2012
A new Boston University School of Medicine (BUSM) study has found that improving Human papillomavirus (HPV) vaccination rates in black women may require culturally sensitive approaches that address ethnic-specific barriers. The findings are published online in the November/December issue of the journal, Women's Health Issues...
Preschool Children Particularly Vulnerable To Toxic Compounds In Food
11/15/2012
In a sobering study published in the journal Environmental Health, researchers at UC Davis and UCLA measured food-borne toxin exposure in children and adults by pinpointing foods with high levels of toxic compounds and determining how much of these foods were consumed...
Cancers arise when a normal cell acquires a mutation in a gene that regulates cellular growth or survival. But the particular cell this mutation happens in - the cell of origin - can have an enormous impact on the behavior of the tumor, and on the strategies used to treat it. Robert Wechsler-Reya, Ph.D...
Can The Addition Of Radiolabeled Treatments Improve Outcomes In Advanced Metastatic Disease?
11/15/2012
Radiolabeled agents are powerful tools for targeting and killing cancer cells and may help improve outcomes and lengthen survival times of patients with advanced disease that has spread beyond the initial tumor site...
Loss Of Essential Blood Cell Gene Leads To Anemia
11/15/2012
Scientists at the University of Georgia, Harvard Medical School and the University of Utah have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood. The study was published online and will be in the Nov...
Terminally ill cancer patients who have an early talk with their physician about care at the end-of-life are less likely to receive aggressive therapy - and more likely to enter hospice care - than patients who delay such discussions until the days and weeks before death, a new study by Dana-Farber Cancer Institute researchers suggests...