Cometriq (Cabozantinib) For Medullary Thyroid Cancer Approved By FDA
11/30/2012
Cometriq (cabozantinib) has been approved by the FDA for the treatment of progressive medullary thyroid cancer that has metastasized - spread to other parts of the body. Medullary thyroid cancer, a rare form of thyroid cancer, starts off in the cells that make calcitonin, a hormone which regulates calcium levels in the blood and bones...
KRAS and BRAF Mutation Screening In Metastatic Colorectal Cancer Costly In Relation To Benefits
11/30/2012
Researchers report that screening for KRAS and BRAF mutations can reduce the cost of anti-EGFR treatment for metastatic colorectal cancer but with a very small reduction in overall survival according to a new study published on November 28 in the Journal of the National Cancer Institute...
Combined RB And PTEN Loss Identifies DCIS Primed For Invasive Breast Cancer
11/30/2012
The combined loss of two tumor suppressor genes, retinoblastoma (RB) and phosphatase and tensin homolog (PTEN) was shown to be strongly associated with progression of DCIS to invasive breast cancer, according to a study published November 28 in the Journal of the National Cancer Institute...
The Most Resistant Types Of Chronic Myeloid Leukemia May Be Defeated By Ponatinib
11/30/2012
A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine. All 12 patients in the trial with chronic phase CML and the T315I mutation had a complete hematologic response (absence of CML cells in the blood) after treatment with ponatinib...
First Success Reported Of Targeted Therapy In Most Common Non-Small Cell Lung Cancer
11/30/2012
A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer...
Scientists Uncover A Novel Cooperative Effort To Halt Cancer Metastatis
11/30/2012
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site...
Specifit Receptor Sparks Prostate Cancer Progression
11/30/2012
Prostate cancer presents a dilemma for patients and the physicians who treat them. Which cancers are essentially indolent and present no risk and which are life threatening? Which can be watched and which need aggressive treatment? Drs...
Researchers report that screening for KRAS and BRAF mutations can reduce the cost of anti-EGFR treatment for metastatic colorectal cancer but with a very small reduction in overall survival according to a new study published in the Journal of the National Cancer Institute...
Researchers found that aspirin use is associated with a decreased risk of developing hepatocellular carcinoma and death from chronic liver disease (CLD), according to a study published in the Journal of the National Cancer Institute. Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, occurs mainly among patients with CLD...
Cancer Screening Via Blood Test And Gene Sequencing
11/30/2012
Scientists at the Johns Hopkins Kimmel Cancer Center have combined the ability to detect cancer DNA in the blood with genome sequencing technology in a test that could be used to screen for cancers, monitor cancer patients for recurrence and find residual cancer left after surgery...