Potent Anticancer Effect Achievewith Engineered T Cell Therapy On First Use In Children
12/12/2012
By reprogramming a 7-year-old girl's own immune cells to attack an aggressive form of childhood leukemia, a pediatric oncologist has achieved a complete response in his patient, who faced grim prospects when she relapsed after conventional treatment. The innovative experimental therapy used bioengineered T cells, custom-designed to multiply rapidly in the patient, and then destroy leukemia cells...
The Internet Can Reduce Fatalistic View Of Cancer
12/12/2012
Many Americans have fatalistic views on cancer prevention - they believe that getting cancer is a matter of luck or fate. Recent research, published in the Journal of Communication, found that people who use the internet to inquire about their health are more likely to have a positive outlook on cancer prevention and diagnosis...
Terminal Cancer Patients Watch Educational Video To Help Them Decide Whether Or Not To Receive CPR
12/12/2012
Patients with terminal cancer who viewed a three-minute video demonstrating cardiopulmonary resuscitation (CPR) were less likely to indicate a preference for receiving CPR in the event of an in-hospital cardiac arrest than were patients who only listened to a verbal description of the procedure...
Sickle Cell Patients Rely On ER Into Adulthood
12/12/2012
Patients with sickle cell disease rely more on the emergency room as they move from pediatric to adult health care, according to researchers at Washington University School of Medicine in St. Louis. An analysis of Medicaid data of more than 3,200 patients with sickle cell disease shows that emergency room visits tripled from age 15 to age 24...
For Patients With Sickle Cell Disease, New Studies Reveal Critical Insights To Improve Care
12/12/2012
Research unveiling key gaps in continuity of care for sickle cell patients transitioning from pediatric to adult care were during the 54th Annual Meeting of the American Society of Hematology (ASH). Sickle cell disease (SCD) is an inherited, chronic blood disorder affecting between 90,000 and 100,000 Americans...
Older Leukemia Patients Benefit From Reduced Intensity Regimen Prior To Marrow Transplant
12/12/2012
A new study led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J...
More Than 2 Years After Engineered T Cell Therapy, Leukemia Patients Remain In Remission
12/12/2012
Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the therapy, which was pioneered by scientists in the Perelman School of Medicine at the University of Pennsylvania...
Hope For Patients With Hard-To-Treat Blood Disorders
12/12/2012
Encouraging safety and efficacy data on novel and emerging therapies presented at the 54th Annual Meeting of the American Society of Hematology (ASH) signal an important step forward in the development of treatment strategies for patients with hard-to-treat leukemia, myeloma, and myelofibrosis...
Scientists Target DNA Repair To Eradicate Leukemia Stem Cells
12/12/2012
Despite treatment with imatinib, a successful drug that targets chronic myeloid leukemia (CML), a deadly type of cancer, some patients may continue to be at risk for relapse because a tiny pool of stem cells is resistant to treatment and may even accumulate additional genetic aberrations, eventually leading to disease progression and relapse...
Algae Engineered By Biologists To Make Complex Anti-Cancer 'Designer' Drug
12/12/2012
Biologists at UC San Diego have succeeded in genetically engineering algae to produce a complex and expensive human therapeutic drug used to treat cancer...