Surprising Discovery About Stem Cells Reveals How A Common Breast Cancer Evades Treatment
12/17/2012
A new study reveals a surprising paradox about stem cells in breast cancer: one whose discovery may explain how a common breast cancer evades treatment, and improve diagnosis and treatment of the disease...
Ruxolitinib Produces Durable Improvements In Patients With Myelofibrosis
12/17/2012
ATLANTA - Ruxolitinib reduces splenomegaly and other symptoms commonly associated with myelofibrosis, and the results are maintained for at least two years, according to results released at the 54th American Society of Hematology Annual Meeting...
Drug Approved To Treat Rare Forms Of Leukemia
12/17/2012
A new drug used to treat patients with chronic myeloid leukemia (CML) and Philadelphia chromosome positive acute leukemia (Ph+ ALL) has just received approval from the U.S. Food and Drug Administration...
The Age Of Chronic Leukemia Patients May Affect Therapy
12/17/2012
Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James)...
Approximately one in 20 patients with non-small cell lung carcinoma (NSCLC) has chromosomal aberrations targeting the anaplastic lymphoma kinase (ALK) gene. This has considerable implications for treatment because these patients are highly responsive to ALK-specific kinase inhibitors such as crizotinib. However, current diagnostic tests have limitations...
Family History Of Colorectal Cancer May Increase Risk For Aggressive Form Of The Disease
12/17/2012
When people with a family history of colorectal cancer develop the disease, their tumors often carry a molecular sign that the cancer could be life-threatening and may require aggressive treatment, Dana-Farber Cancer Institute scientists report in a new study...
Younger women who wait at least 15 years after their first menstrual period to give birth to their first child may reduce their risk of an aggressive form of breast cancer by up to 60 percent, according to a Fred Hutchinson Cancer Research Center study. The findings, by Christopher I. Li, M.D., Ph.D...
Common Childhood Leukemia May Be Treated With Vegetable Compound
12/17/2012
It looks like your mother was on to something when she said, "Eat your vegetables!" A concentrated form of a compound called sulforaphane found in broccoli and other cruciferous vegetables has been shown to reduce the number of acute lymphoblastic leukemia cells in the lab setting, said researchers at Baylor College of Medicine. The findings appear in PLOS ONE...
Synthetic Chemistry And Drug Development
12/17/2012
In science's equivalent of ascending Mt. Everest, researchers are reporting success in one of the most difficult challenges in synthetic chemistry - a field in which scientists reproduce natural and other substances from jars of chemicals in a lab...
Raccoon Polyomavirus May Provide Cancer Clues
12/17/2012
Rare brain tumors emerging among raccoons in Northern California and Oregon may be linked to a previously unidentified virus discovered by a team of researchers, led by scientists from the University of California, Davis. Their findings, published in the journal Emerging Infectious Diseases, could lead to a better understanding of how viruses can cause cancer in animals and humans...