Knowing How Cells Know They Aren't Upside Down May Help Fight Cancer
1/02/2013
The tops and bottoms of cells do different jobs, and healthy organs and tissue contain well-organized cells that are the right way up. One of the first signs of cancer is when cells become disorganized and can end up upside down. Now researchers in the UK have discovered how cells know when they are the right way up, and suggest this knowledge will help in the fight against cancer...
Game Changing Diagnostic & Prognostic Prostate Cancer Genetic Tests Revealed By Jefferson
1/02/2013
Researchers at the Kimmel Cancer Center at Jefferson (KCC) have developed potentially game-changing diagnostic and prognostic genetic tests shown to better predict prostate cancer survival outcomes and distinguish clinically-relevant cancers. The team, led by Richard G. Pestell, M.D., Ph.D...
Protein Kinase Akt Identified As Arbiter Of Cancer Stem Cell Fate, According To Penn Study
1/02/2013
The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death...
Robotic-Assisted Radical Bladder Surgery Potentially Benefits Bladder Cancer Patients
1/02/2013
About 30 percent of the more than 70,000 bladder cancer cases expected in 2012 are muscle invasive. In such cases, radical cystectomy is the preferred treatment. In a pilot trial, a team of investigators assessed the efficacy of open radical cystectomy (ORC) vs. robotic-assisted laparoscopic radical cystectomy (RARC)...
Gene Expression Improves The Definition Of A Breast Cancer Subtype
1/02/2013
Gene expression in breast cancer provides valuable biological information for better determining the diagnosis, treatment, risk of relapse and survival rate. However, the most common form of characterizing breast cancer is by histopathological techniques...
Better Approach To Treating Deadly Melanoma Identified By Scientists
1/01/2013
Scientists at The University of Manchester have identified a protein that appears to hold the key to creating more effective drug treatments for melanoma, one of the deadliest cancers...
Better Approach To Treating Deadly Melanoma Identified By Scientists
1/01/2013
Scientists at The University of Manchester have identified a protein that appears to hold the key to creating more effective drug treatments for melanoma, one of the deadliest cancers...
Breast Cancer Diagnosis Could Benefit Greatly From Spectroscopy
12/31/2012
The analysis of small deposits of calcium in breast tissue can help differentiate cancerous and benign tumors, but it is sometimes not easy to make such a diagnosis. Now a team of researchers in the US believes a new method that uses a special type of spectroscopy to locate calcium deposits during a biopsy, could greatly improve the accuracy of diagnosis...
New Technique Catalogs Lymphoma-Linked Genetic Variations
12/31/2012
As anyone familiar with the X-Men knows, mutants can be either very good or very bad -- or somewhere in between. The same appears true within cancer cells, which may harbor hundreds of mutations that set them apart from other cells in the body; the scientific challenge has been to figure out which mutations are culprits and which are innocent bystanders...
FAK Inhibitor Proves Effective Against Brain Tumors In Preclinical Studies, RPCI-Led Study Shows
12/31/2012
Anticancer effects of small-molecule inhibitor CFAK-Y15 even more pronounced as part of combination therapy Researchers from Roswell Park Cancer Institute (RPCI) have published findings from a preclinical study assessing the effectiveness of a small-molecule inhibitor, CFAK-Y15, in treating some brain cancers...